柴胡芩连汤治疗前庭性偏头痛的临床研究

发布时间：2018-04-18 21:24

本文选题：前庭性偏头痛 + 眩晕障碍量表　；参考：《长春中医药大学》2016年硕士论文

【摘要】：目的:以疏肝和胃为切入点,观察柴胡芩连汤治疗前庭性偏头痛的临床疗效,为中医药治疗前庭性偏头痛提供新的思路和方法。方法:选取80例前庭性偏头痛患者,随机分为治疗组与对照组各40例,开展随机对照临床研究。治疗组给予口服柴胡芩连汤,对照组给予口服甲磺酸倍他司汀片,疗程均为4周。观察两组治疗前后的临床总疗效、眩晕障碍量表(DHI)、健康状况量表(SF-36)及眩晕发作次数、眩晕发作持续时间的变化。治疗后随访3个月,观察两组眩晕复发情况。结果:治疗4周后,最终完成临床观察患者共76例(治疗组脱落1例,对照组脱落3例),对该76例患者临床观察数据进行统计分析。1.治疗组的临床总疗效为82.05%,对照组的临床总疗效为72.68%,治疗组优于对照组,两组比较差异有统计学意义(P㩳0.05);治疗组及对照组的眩晕障碍量表(DHI)积分、健康状况量表(SF-36)积分及眩晕发作次数、眩晕发作持续时间均有所改善,且两组组内比较差异具有统计学意义(P0.05),说明用药后患者各项疗效指标均优于用药前;组间比较,治疗组较对照组健康状况量表积分、眩晕发作次数、眩晕发作持续时间改善明显,治疗组优于对照组,且差异有统计学意义(P0.05)。眩晕障碍量表积分较对照组改善无明显变化,差异无统计学意义(P0.05)。2.随访3个月后,两组患者的眩晕发作次数、眩晕发作持续时间组间比较差异有统计学意义(P0.05),治疗组的眩晕复发状况明显优于对照组。结论:柴胡芩连汤可以有效缓解前庭性偏头痛患者的中医症状,减轻眩晕发作程度,提高患者生活质量,且能够减少眩晕发作次数、缩短眩晕发作持续时间,有效控制眩晕症状的复发,远期疗效较好,值得临床推广。
[Abstract]:Objective: to observe the clinical effect of Chaihu Qinlian decoction in treating vestibular migraine and provide new ideas and methods for treating vestibular migraine with traditional Chinese medicine.Methods: 80 patients with vestibular migraine were randomly divided into treatment group (n = 40) and control group (n = 40).The treatment group was treated with Chaihu Qinlian decoction and the control group with betastatin mesylate for 4 weeks.The changes of total clinical efficacy, dizziness scale, SF-36), the number of vertigo attacks and the duration of vertigo attack were observed before and after treatment in the two groups.The patients were followed up for 3 months to observe the recurrence of vertigo in the two groups.Results: after 4 weeks of treatment, 76 patients (1 case in the treatment group and 3 cases in the control group) finished the clinical observation. The clinical observation data of the 76 cases were statistically analyzed.The total clinical efficacy of the treatment group was 82.05 and that of the control group was 72.68. The treatment group was superior to the control group, and the difference between the two groups was statistically significant.The scores of SF-36), the frequency of vertigo attack and the duration of vertigo attack were improved, and the difference between the two groups was statistically significant (P 0.05).Compared with the control group, the scores of health status scale, the frequency of vertigo attack and the duration of vertigo attack in the treatment group were significantly improved, and the treatment group was better than the control group, and the difference was statistically significant (P 0.05).Compared with the control group, the score of vertigo disorder scale had no significant change, and the difference was not statistically significant (P 0.05).After 3 months follow-up, there were significant differences in the number of vertigo attacks and the duration of vertigo attacks between the two groups. The relapse status of vertigo in the treatment group was significantly better than that in the control group (P 0.05).Conclusion: Chaihu Qinlian decoction can effectively relieve the symptoms of vestibular migraine, reduce the degree of vertigo attack, improve the quality of life of the patients, reduce the frequency of vertigo attack and shorten the duration of vertigo attack.Effective control of the recurrence of vertigo symptoms, long-term results are better, worthy of clinical promotion.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.7

【参考文献】