清肝宁胃汤治疗原发性胆汁反流性胃炎（肝胃郁热证）的临床观察

发布时间：2018-04-22 05:17

本文选题：原发性胆汁反流性胃炎 + 肝胃郁热证　；参考：《黑龙江中医药大学》2016年硕士论文

【摘要】：研究目的：本课题主要研究谢晶日教授自拟清肝宁胃汤治疗原发性胆汁反流性胃炎(肝胃郁热证)的临床疗效,为日后临床应用提供客观依据。研究方法：选择符合原发性胆汁反流性胃炎(肝胃郁热证型)患者38例,均在2015年1月至2016年1月就诊于黑龙江中医药大学第一附属医院门诊,入选38例患者给予清肝宁胃汤治疗,药品由黑龙江中医药大学附属第一医院天江免煎药局统一提供,150毫升温开水冲服,每日2次,分早晚饭前30分钟口服,连续服用8周为1个疗程,观察患者治疗前后临床疗效、症状积分、胃镜的变化,对结果进行统计学分析。结果：清肝宁胃汤治疗原发性胆汁反流性胃炎临床总有效率为86.84%,胃黏膜相的总有效率是89.47%,胆汁返流的总有效率是94.74%,中医证候总有效率是89.47%。在中医证候总积分方面,治疗后较治疗前显著下降(P0.01)。在中医证候单项积分方面,治疗后在患者胃痛或痛窜两胁,胃脘痞满,情志不畅,反酸、烧心,口苦、口臭,恶心、呕吐,嗳气和大便干结方面,积分均较治疗前有所下降,有统计学差异(P0.01)。结论：1、清肝宁胃汤能够改善肝胃郁热型PBRG患者的中医证候表现。2、清肝宁胃汤能够改善肝胃郁热型PBRG患者的胃镜下炎症病变和胆汁反流情况。
[Abstract]:Objective: to study the clinical effect of Professor Xie Jingri on treating primary bile reflux gastritis (liver-stomach stagnation heat syndrome) by using Qinggan Ningwei decoction, and to provide objective basis for clinical application in the future. Methods: a total of 38 patients with primary bile reflux gastritis (liver-stomach stagnation and heat syndrome) were selected from January 2015 to January 2016 in the outpatient clinic of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine. Thirty-eight patients were treated with Qinggan Ningwei decoction. The medicine was administered by Tianjiang Medical Bureau of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine with 150 milliliters of warm boiled water, twice a day, orally 30 minutes before morning and evening. The clinical effect, symptom score and gastroscope were observed before and after 8 weeks of continuous treatment. The results were statistically analyzed. Results: the total effective rate of Qinggan Ningwei decoction in the treatment of primary bile reflux gastritis was 86.84, the total effective rate of gastric mucosa was 89.47, the total effective rate of bile regurgitation was 94.74 and the total effective rate of TCM syndrome was 89.47. In the aspect of the total integral of TCM syndromes, the value of P0.01 was significantly lower after treatment than that before treatment. In the single integral of TCM syndromes, after treatment, the scores of patients with stomachache or pain channeling into both sides, epigastric fullness, unobstructed mood, acid regurgitation, heartburn, bitter mouth, bad breath, nausea, vomiting, belching and stool dry knots were all lower than before treatment. There was statistical difference (P 0.01). Conclusion: W1, Qinggan Ningwei decoction can improve the TCM syndromes of PBRG patients with liver and stomach stagnation heat, and Qinggan Ningwei decoction can improve the inflammation and bile regurgitation under gastroscope in patients with PBRG with liver and stomach stagnation heat.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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