补阳还五汤联合穴位注射治疗缺血性中风恢复期的临床研究

发布时间：2018-04-22 09:42

本文选题：补阳还五汤 + 穴位注射　；参考：《广西中医药大学》2017年硕士论文

【摘要】：目的:观察补阳还五汤联合穴位注射对缺血性中风恢复期气虚血瘀证的临床疗效,客观评价其有效性和安全性,为该治疗方案的临床应用提供依据。研究方法:临床研究共收集病例81例,按随机数字表分为治疗组41例,对照组40例,治疗组在西医常规治疗的基础上予补阳还五汤联合穴位注射治疗,对照组采用西医常规治疗,治疗疗程为28天。选取中医中风病证候疗效评价量表、美国国立卫生研究员卒中量表(NIHSS)、日常生活活动能力量表(ADL)、血脂检测为疗效评价指标,观察记录纳入临床研究的治疗组及对照组患者治疗前后各疗效评价指标的变化。运用spss19.0统计软件,对数据进行统计分析。结果:1、评价中医证候疗效改善情况,治疗组总有效率达75.6%,对照组总有效率为52.5%,两组治疗后中医证候疗效结果比较(?2=4.71,P0.05),差异有统计学意义,治疗组疗效优于对照组;2、评价中医证候积分改善情况,治疗组治疗前后组间比较(t=5.40,P0.01),对照组治疗前后比较(t=2.18,P0.05),治疗后治疗组与对照组比较(t=-5.96,P0.01),治疗组与对照组均能改善中医证候积分,且治疗组改善效果优于对照组;3、评价神经功能缺损改善情况,治疗组治疗前后比较(t=3.19,P0.01),对照组治疗前后比较(t=4.65,P0.01),治疗后治疗组与对照组比较(t=-3.63,P0.01),治疗组与对照组均显著能改善神经功能缺损程度,且治疗组改善效果优于对照组;4、评价日常生活能力改善情况,治疗组治疗前后组间比较(t=-7.76,P0.01),对照组治疗前后组间比较(t=-2.11,P0.05),治疗后治疗组与对照组比较(t=-4.52,P0.01),治疗组与对照组均能提高患者的日常生活能力,且治疗组改善效果优于对照组;5、评价血脂TC、TG、HDL-C、LDL-C水平善情况,治疗组治疗前后组间比较(t=4.15,P0.01、t=4.68,P0.01、t=-2.61,P0.05、t=6.62,P0.01),对照组治疗前后比较(t=2.19,P0.05、t=0.75,P0.05、t=-2.10,P0.05、t=2.10,P0.05),治疗后治疗组与对照组比较(t=-3.02,P0.01、t=-2.97,P0.01、t=2.30,P0.05、t=-7.48,P0.01),治疗组与对照组均能改善患者的血脂水平,且治疗组优于对照组。结论:1、补阳还五汤联合穴位注射治疗能有效地改善缺血性中风恢复期气虚血瘀证患者中医临床证候疗效;2、补阳还五汤联合穴位注射治疗较西医常规治疗在改善缺血性中风恢复期气虚血瘀证患者神经功能缺损程度、日常生活能力及血脂水平方面具有更好的疗效。
[Abstract]:Objective: to observe the clinical effect of Buyang Huanwu decoction combined with acupoint injection on qi deficiency and blood stasis syndrome of ischemic apoplexy in convalescence, and to evaluate its efficacy and safety objectively. Methods: a total of 81 cases were collected and randomly divided into treatment group (n = 41) and control group (n = 40). The treatment group was treated with Buyang Huanwu decoction combined with acupoint injection on the basis of routine western medicine treatment. The control group was treated with routine western medicine for 28 days. We selected TCM Stroke Syndrome Evaluation scale, National Health Research Stroke scale, ADL activity scale and Blood Lipid Test as curative Evaluation Index. To observe the changes of the curative effect evaluation indexes before and after treatment in the treatment group and the control group, which were included in the clinical study. Spss19.0 statistical software is used to analyze the data. Results the total effective rate of the treatment group was 75.66.The total effective rate of the control group was 52.5. The curative effect of traditional Chinese medicine syndrome was compared between the two groups after treatment, and the difference was statistically significant. The curative effect of the treatment group was better than that of the control group, and the improvement of TCM syndrome score was evaluated. The comparison between the treatment group and the control group was made between the two groups before and after treatment, and the comparison between the control group and the control group was made before and after treatment. After treatment, the treatment group was better than the control group, and the treatment group was better than the control group, and the treatment group and the control group could both improve the TCM syndromes score. The improvement effect of the treatment group was better than that of the control group. The comparison between the treatment group and the control group was made before and after treatment, and the comparison between the treatment group and the control group was made before and after treatment. After treatment, the treatment group was compared with the control group, and the treatment group was compared with the control group. Both the treatment group and the control group could significantly improve the degree of nerve function defect, and compared with the control group before and after treatment, the treatment group and the control group could significantly improve the degree of nerve function defect. The improvement effect of the treatment group was better than that of the control group, and the improvement of daily living ability was evaluated. The comparison between the treatment group and the control group before and after treatment, the comparison between the two groups before and after treatment, the comparison between the two groups before and after treatment, the comparison between the treatment group and the control group before and after treatment, and the comparison between the treatment group and the control group before and after treatment, and the comparison between the treatment group and the control group. Both the treatment group and the control group could improve the daily life ability of the patients. The improvement effect of the treatment group was better than that of the control group. Conclusion 1, Buyang Huanwu decoction combined with acupoint injection can effectively improve the curative effect of TCM syndromes in patients with Qi deficiency and blood stasis syndrome of ischemic apoplexy in convalescence stage. Buyang Huanwu decoction combined with acupoint injection therapy can improve deficiency compared with routine western medicine treatment. The degree of nerve function defect in patients with Qi deficiency and blood stasis syndrome in recovery period of hemorrhagic apoplexy, The ability of daily life and the level of blood lipid have better curative effect.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R277.7

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