中医特色慢病管理对维持溃疡性结肠炎缓解期的疗效研究

发布时间：2018-04-25 05:41

本文选题：溃疡性结肠炎 + 缓解期　；参考：《中华中医药杂志》2017年07期

【摘要】：目的:对中医特色慢病管理治疗溃疡性结肠炎(UC)的近期、远期疗效、预防复发及其安全性作出科学评价。方法:采用随机、对照的方法,选择UC缓解期患者60例,随机分为两组:治疗组给予中医特色慢病管理模式,对照组给予目前西医对维持缓解UC有效的所有药物作为对照,其中,以艾迪莎(美沙拉嗪)为主。疗程均为6个月,每月随访记录症状,主要观察临床症状疗效、复发率、临床活动指数及内镜指数的变化、生活质量、不良反应和费用。结果:治疗6个月后,治疗组与对照组相比,复发率相当且不良反应少,改善症状持久稳定,并改善贫血等全身症状,提高肠道黏膜愈合质量,减少医疗费用,提高生活质量。结论:中医慢病管理治疗UC缓解期有一定的优势和发展潜力,具有价廉、有效、安全等优点,值得进一步深入研究、探讨并推广。
[Abstract]:Objective: to evaluate the short term and long term curative effect, prevention and safety of ulcerative colitis (UC) treated by management of characteristic chronic diseases of traditional Chinese medicine (TCM). Methods: sixty UC patients in remission period were randomly divided into two groups: the treatment group was treated with traditional Chinese medicine (TCM) characteristic chronic disease management model, and the control group was treated with all the drugs that were effective in maintaining the remission of UC. Among them, the main is Edessa (Mesalazine). The course of treatment was 6 months. The symptoms were recorded every month. The changes of clinical symptoms, recurrence rate, clinical activity index and endoscopic index, quality of life, adverse reactions and expenses were observed. Results: after 6 months of treatment, the recurrence rate of the treatment group was equal to that of the control group, and the adverse reactions were less, the symptoms were improved and the systemic symptoms such as anemia were improved, the healing quality of intestinal mucosa was improved, the medical expenses were reduced, and the quality of life was improved. Conclusion: the management of chronic diseases in TCM has some advantages and development potential in the remission period of UC. It has the advantages of cheap, effective and safe, which is worthy of further study, discussion and popularization.
【作者单位】：武汉市中西医结合医院消化科;广东省中医院广州中医药大学第二临床医学院;
【基金】：国家中医临床研究基地业务建设科研专项课题(No.JDZX2012085)~~
【分类号】：R259

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