脑脉舒康胶囊治疗高脂血症合并缺血性脑卒中恢复期的临床观察

发布时间：2018-04-27 07:24

本文选题：脑脉舒康胶囊 + 高脂血　；参考：《河南中医药大学》2016年硕士论文

【摘要】：目的:观察脑脉舒康胶囊治疗高脂血症合并缺血性脑卒中恢复期,中医辨证属气阴两虚型的临床疗效。方法:根据病例纳入标准,将70例辨证为气阴两虚型高脂血症合并缺血性脑卒中的患者,采用区组随机的方法将治疗组和对照组按1:1的比例分为治疗组、对照组各35例。对照组根据病情合理服用西药,治疗组在对照组基础上加服脑脉舒康胶囊。符合要求的病人入组后,每人用药共8周即56天。观察治疗前后,患者中医证候、日常生活能力积分、神经功能缺损等方面的改善情况。所得数据都均采用spass20.0软件进行分析。结果:(1)血脂四项:治疗组、对照组总胆固醇、低密度脂蛋白同疗前相比均降低,且疗后治疗组总胆固醇、低密度脂蛋白同对照组相比有差异。(2)神经功能缺损、中医症候、血流变全血粘度、血浆粘度、血管内皮功能ET评分:两组疗后评分较疗前均降低,同治疗前相比均有显著性差异,且两组疗后组间比有差异。(3)日常生活能力、NO评分:两组治疗后的积分均升高,同治疗前相比均有显著性差异,且两组疗后组间比有差异。结论:脑脉舒康胶囊在治疗高脂血合并缺血性脑卒中恢复期气阴两虚型有明显优势。脑脉舒康胶囊可能通过改善血管内皮细胞功能,降低血粘度,改善血脂,减少高脂血合并缺血性脑卒中恢复期患者的神经功能缺损,提高患者的日常生活能力,从而促进患者的康复。
[Abstract]:Objective: to observe the clinical effect of Naomai Shukang capsule in treating hyperlipidemia with ischemic stroke. Methods: 70 patients with hyperlipidemia combined with ischemic stroke were divided into treatment group (35 cases) and control group (35 cases) according to 1:1 ratio. The control group took western medicine reasonably according to the condition, and the treatment group took Naomai Shukang capsule on the basis of the control group. The patients who met the requirements were treated for a total of 8 weeks (56 days). The improvement of TCM syndromes, ADL score and neurological deficit were observed before and after treatment. All the data are analyzed by spass20.0 software. Results 1) four items of blood lipids: total cholesterol and low density lipoprotein in treatment group and control group were all lower than before treatment, and there were differences in total cholesterol and low density lipoprotein between treatment group and control group after treatment. Blood rheology whole blood viscosity plasma viscosity et score of vascular endothelial function: after treatment the scores of the two groups were lower than those before treatment and there were significant differences between the two groups before and after treatment. There was significant difference between the two groups after treatment, and there was a difference between the two groups after treatment, and there was a difference between the two groups after treatment. Conclusion: Naomai Shukang capsule has obvious advantages in the treatment of hyperlipidemia combined with ischemic stroke. Naomai Shukang capsule may improve the function of vascular endothelial cells, reduce blood viscosity, improve blood lipid, reduce the neurological deficit of patients with hyperlipidemia combined with ischemic stroke, and improve the ability of daily life of patients. So as to promote the recovery of patients.
【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259;R277.7

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