应用红外线眼动仪观察针刺治疗眼肌麻痹急性效应的研究

发布时间：2018-04-28 20:20

本文选题：眼肌麻痹 + 针刺　；参考：《云南中医学院》2017年硕士论文

【摘要】：目的:应用红外眼动仪研究针刺治疗眼肌麻痹的急性效应(针刺前后1小时),探讨针刺急性效应与长期效应(间隔2-5天或更长时间前后数据的对比,反映的是这段时间内针刺的一个积累效应)之间的相关性,对针刺治疗眼肌麻痹的疗效作出客观评价,为眼肌麻痹的治疗提供理论依据,并探索针刺治疗眼肌麻痹的相关机理。方法:1.选取眼肌麻痹患者20例,分别在针刺前后记录眼动数据,分析对比针刺前后眼动数据,观察针刺急性效应,其中,20例患者中只有6例患者符合条件入选试验评估。并且将急性针刺数据和长期针刺数据做线性回归,观察针刺急性效应与长期效应间的相关性。2.治疗方法:采用传统针灸针刺治疗,依据病人病变眼肌不同选取不同的针刺穴位,但同一眼肌麻痹患者所选主要穴位相同。针刺前运用红外线眼动仪对眼肌麻痹患者进行眼动数据采集,针刺后又立即给予测量采集。应用红外线眼动仪对眼肌麻痹患者进行测量时,每次测量的时间根据患者成功次数而定,即successful number为120次(眼动仪能诱导眼球运动,其对眼球运动的康复治疗作用尚不明确,该次数是能避免其对眼球运动恢复的干扰且能更好的分析眼动数据的改变)。若同时患有其他并发症或伴发症,则予相应的治疗,如高血压降压、高血脂降血脂、高血糖降糖、甲状腺功能减退者改善其功能等。3.使用红外线眼动仪收集患者眼球运动功能数据,选择被试者单次扫视运动双眼的幅度差、峰速度差和时间差作为评估被试患者眼球运动功能的基本参数,其中幅度差和峰速度差又可以分为水平(X)和垂直(Y)两个分量,故每个被试者单次单方向总共有(1)X分量幅度差、(2)Y分量幅度差、(3)X分量峰速度差、(4)Y分量峰速度差和(5)时间差五个评价参数,选择每个方向记录20-30次扫视数据作为观察指标。结果:1.针刺急性效应:6例患者共收集60组急性针刺数据,分析数据发现针刺前后五项眼动指标均有显著变化的有3组,均没有显著变化的2组,有48组针刺前后至少有3项数据发生显著变化,有7组仅有1-2项数据发生显著变化。2.急性效应和长期效应的相关性:将60组急性针刺数据与16组长期针刺数据对比,发现一半的急性数据与长期数据有较好的正相关。结论:应用红外眼动仪研究针刺治疗眼肌麻痹的急性效应,发现运用针刺治疗眼肌麻痹患者其眼球运动功能发生显著变化,针刺治疗的急性效应与长期效应呈正相关。
[Abstract]:Objective: to study the acute effect of acupuncture on ophthalmoplegia (1 hour before and after acupuncture) by using infrared eye movement instrument, and to explore the comparison between the acute effect of acupuncture and the long-term effect (interval 2-5 days or more) before and after acupuncture. It reflects the correlation between the cumulative effect of acupuncture in this period of time. The objective evaluation of the therapeutic effect of acupuncture on ophthalmoplegia provides theoretical basis for the treatment of ophthalmoplegia and explores the related mechanism of acupuncture treatment of ophthalmoplegia. Method 1: 1. Twenty patients with ophthalmoplegia were selected to record the data of eye movement before and after acupuncture, to analyze and compare the data of eye movement before and after acupuncture, and to observe the acute effect of acupuncture. The correlation between acute acupuncture effect and long-term acupuncture effect was observed by linear regression of acute acupuncture data and long-term acupuncture data. Methods: traditional acupuncture was used to treat different acupuncture points according to the pathological changes of the eye muscles, but the main points were the same as the main points selected by the patients with ocular paralysis. Before acupuncture, infrared eye movement instrument was used to collect eye movement data of patients with ophthalmoplegia. When using infrared eye movement instrument to measure ophthalmoplegia patients, the time of each measurement is determined by the successful times of the patients, that is, successful number is 120 times (eye movement instrument can induce eye movement, its rehabilitation effect on eye movement is not clear. This frequency can avoid the disturbance of eye movement recovery and better analyze the change of eye movement data. If there are other complications or complications at the same time, the corresponding treatment is given, such as hypertension, hyperlipidemia, hyperglycemia, hypothyroidism, etc. The data of eyeball movement function were collected by infrared eye movement instrument, and the amplitude difference, peak velocity difference and time difference of single scan movement were selected as the basic parameters to evaluate the eye movement function of the subjects. The amplitude difference and the peak velocity difference can be divided into two components: horizontal X) and vertical Y). Therefore, there are five evaluation parameters in a single direction of each subject, namely, the amplitude difference of one X component and the amplitude difference between two and two y components, and the peak velocity difference of three X components, and the peak velocity difference of 4y component and the peak velocity difference of 5). 20-30 scan data are recorded in each direction as the observation index. The result is 1: 1. 60 groups of acute acupuncture data were collected from 6 patients with acute acupuncture effect. The data showed that there were significant changes in the five eye movement indexes before and after acupuncture in 3 groups, and no significant changes were found in the two groups. At least 3 items of data changed significantly before and after acupuncture in 48 groups, and only 1-2 items changed significantly in 7 groups. Correlation between acute and long-term effects: 60 groups of acute acupuncture data were compared with 16 groups of long-term acupuncture data, and half of the acute data were positively correlated with long-term data. Conclusion: the acute effect of acupuncture on ophthalmoplegia was studied by using infrared eye movement instrument. It was found that the eye movement function of patients with ophthalmoplegia treated by acupuncture was significantly changed, and the acute effect of acupuncture was positively correlated with long-term effect.
【学位授予单位】：云南中医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R246.82

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