手足浸泡方治疗手足综合征临床研究

发布时间：2018-04-30 20:11

本文选题：手足综合征 + 手足浸泡方　；参考：《河南中医》2017年04期

【摘要】：目的:观察手足浸泡方治疗化疗后手足综合征(hand-foot syndrome,HFS)的临床疗效。方法:将79例HFS患者随机分为对照组A 30例、对照组B 19例和治疗组30例。各组均给予化疗,化疗开始时即予下述治疗:治疗组予手足浸泡方,对照组A给予质量分数0.3%聚维酮碘,对照组B口服维生素B6。观察各组患者的临床疗效、总化疗时间及治疗前后神经电生理变化情况。结果:对照组A有效率为70.0%,对照组B有效率为63.2%,治疗组有效率为86.7%,三组比较,差异具有统计学意义(P0.05)。治疗组、对照组A、对照组B总化疗时间分别为(4.24±1.02)个月、(6.20±1.35)个月、(6.51±1.41)个月,治疗组与其他两组比较,差异均有统计学意义(P0.05)。各组患者治疗前后神经生理变化比较,差异均无统计学意义(P0.05)。结论:手足浸泡方能显著减轻化疗后手足综合征的症状,提高患者对化疗的耐受性,改善患者的生活质量。
[Abstract]:Objective: To observe the clinical efficacy of hand foot soaking prescription in the treatment of hand-foot syndrome (HFS) after chemotherapy. Methods: 79 cases of HFS patients were randomly divided into control group A 30 cases, control group B 19 cases and treatment group 30 cases. Each group was given chemotherapy, the treatment group was given the following treatment: the treatment group was given hand foot soaking recipe, and the control group A given the mass fraction 0. 3% polyvidone iodine, the control group B oral vitamin B6. observed the clinical efficacy of each group, total chemotherapy time and neurophysiological changes before and after treatment. Results: the control group A effective rate was 70%, the control group B efficiency was 63.2%, the treatment group was 86.7%, three groups, difference was statistically significant (P0.05). The treatment group, the control group A, the control group. The total chemotherapy time in group B was (4.24 + 1.02) months, (6.20 + 1.35) months and (6.51 + 1.41) months, compared with the other two groups, the difference was statistically significant (P0.05). The difference of neurophysiological changes before and after treatment in each group was not statistically significant (P0.05). Conclusion: hand foot and foot immersion can significantly reduce hand foot syndrome after chemotherapy. The symptoms can improve the tolerance of patients to chemotherapy and improve their quality of life.

【作者单位】：湘潭市第二人民医院;
【基金】：湖南省教育厅科研课题(编号:12C0529)
【分类号】：R273

【相似文献】