调肠愈疡汤口服联合灌肠治疗溃疡性结肠炎63例

发布时间：2018-05-05 00:08

本文选题：溃疡性结肠炎 + 调肠愈疡汤　；参考：《河南中医》2017年05期

【摘要】：目的:观察调肠愈疡汤口服联合中药灌肠治疗溃疡性结肠炎的临床疗效、安全性及其对炎症性指标血沉、血小板计数等的影响。方法:将126例湿热内蕴型溃疡性结肠炎患者按就诊先后顺序分成对照组和治疗组各63例,对照组给予美沙拉嗪缓释颗粒(艾迪莎)口服,每日4次,治疗组给予调肠愈疡汤口服及中药方灌肠治疗。两组患者均以4周为1个疗程。观察两组患者治疗前后主要症状证候及血沉、血小板计数等改善情况。结果:治疗后两组中医证候总积分较治疗前显著下降,在降低证候总积分上,治疗组明显优于对照组(P0.01);对照组中医证候显效率为52.38%,治疗组中医证候显效率为92.06%,两组中医证候显效率比较有统计学意义(P0.01);在改善腹痛、里急后重、脓血便等主要症状方面,治疗组优于对照组(P0.05),在改善腹泻方面,两组疗效相当(P0.05);两组治疗后,血沉、血小板计数明显下降,治疗组在降低血沉指标方面,优于对照组(P0.05),在改善血小板计数方面,两组疗效相当(P0.05);治疗期间,两组均未见明显不良反应,仅治疗组开始时偶见恶心、头晕等症状,患者均可耐受,未终止治疗。结论:调肠愈疡汤口服联合中药灌肠治疗湿热内蕴型溃疡性结肠炎疗效显著,无明显不良反应。
[Abstract]:Objective: to observe the clinical efficacy and safety of Tiaochang Yuyang decoction combined with traditional Chinese medicine enema in the treatment of ulcerative colitis and its effect on inflammatory index erythrocyte sedimentation rate and platelet count. Methods: 126 cases of hygrothermal ulcerative colitis were divided into control group (n = 63) and treatment group (n = 63). The treatment group was treated with Tiaochang Yuyang decoction and traditional Chinese medicine enema. The patients in both groups were treated with 4 weeks as a course of treatment. The main symptoms and symptoms, erythrocyte sedimentation rate and platelet count were observed before and after treatment. Results: after treatment, the total score of TCM syndromes in the two groups was significantly lower than that before treatment. The treatment group was obviously superior to the control group (P 0.01), the control group was 52.38 and the treatment group was 92.06. There was significant difference between the two groups in the effective rate of TCM syndrome. The treatment group was superior to the control group (P 0.05). In improving diarrhea, the effect of the two groups was quite high (P 0.05). After treatment, the erythrocyte sedimentation rate (ESR) and the platelet count in the treatment group were significantly decreased. The treatment group was superior to the control group in reducing the ESR index, which was better than that in the control group (P 0.05), and in improving the platelet count. During the treatment period, there were no obvious adverse reactions in both groups, only the symptoms of nausea and dizziness were occasionally seen at the beginning of the treatment group, and the patients could tolerate the treatment without terminating the treatment. Conclusion: Tiaochang Yuyang decoction combined with traditional Chinese medicine enema is effective in the treatment of damp-heat ulcerative colitis with no obvious adverse reactions.
【作者单位】：保定市第二中心医院;
【分类号】：R259

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