养精种玉汤辅以体外受精-胚胎移植对子宫内膜容受性的影响

发布时间：2018-05-05 02:20

本文选题：养精种玉汤 + 体外受精-胚胎移植　；参考：《中医学报》2017年04期

【摘要】：目的:观察养精种玉汤辅以体外受精-胚胎移植技术对子宫内膜容受性的影响。方法:将78例患者随机分为治疗组(39例)和对照组(39例),治疗组于应用促性腺激素释放激素激动剂(gonadotropin-releasing hormone agonist,GnRHa)降调节时加服养精种玉汤,每日1剂,至HCG日停药。对照组采用标准方案治疗不加用中药。观察两组患者肾阴虚证候积分、子宫内膜厚度及形态、HCG日雌激素和孕激素水平、受精率及妊娠率。结果:治疗后治疗组患者肾阴虚证候积分改善情况与对照组比较,差异有统计学意义(P0.05);治疗组治疗后内膜厚度大于治疗前,且与对照组比较,差异有统计学意义(P0.05);两组患者HCG日雌激素、孕激素水平以及受精率比较,差异无统计学意义(P0.05);治疗组妊娠率高于对照组,差异有统计学意义(P0.05)。结论:养精种玉汤可明显增加子宫内膜厚度,改善子宫内膜容受性,提高妊娠率。
[Abstract]:Aim: to observe the effect of Yangjing Jade decoction combined with in vitro fertilization and embryo transfer on endometrial receptivity. Methods: Seventy-eight patients were randomly divided into treatment group (n = 39) and control group (n = 39). In the treatment group, the gonadotropin-releasing hormone agonist GnRHawas added with Yangjing Jieyu decoction once a day until the day of HCG. The control group was treated with standard regimen without Chinese medicine. The syndromes of kidney yin deficiency, endometrial thickness and morphology, estrogen and progesterone levels on HCG day, fertilization rate and pregnancy rate were observed in both groups. Results: compared with the control group, the improvement of the syndrome score of kidney yin deficiency in the treatment group was significantly higher than that in the control group (P 0.05), the thickness of endometrium in the treatment group was greater than that before treatment, and compared with that in the control group. There was no significant difference in estrogen, progesterone and fertilization rate between the two groups. The pregnancy rate in the treatment group was higher than that in the control group, and the difference was statistically significant (P 0.05). Conclusion: YJD can obviously increase endometrial thickness, improve endometrial receptivity and increase pregnancy rate.
【作者单位】：江苏大学附属金坛医院;金坛市中医医院;常州市妇幼保健院;
【基金】：江苏省金坛市科技计划基金项目(JT2013069)
【分类号】：R271.9

【相似文献】