健脾疏肝汤治疗肛门直肠神经官能症（肝郁脾虚证）的临床疗效观察

发布时间：2018-05-05 19:04

本文选题：健脾疏肝汤 + 肝郁脾虚证　；参考：《湖南中医药大学》2016年硕士论文

【摘要】：研究目的本研究的主要目的在于观察健脾疏肝汤治疗肛门直肠神经官能症(肝郁脾虚证)的临床疗效,从而初步评价健脾疏肝汤治疗此病的有效性,为临床治疗此病提供一种可行有效的治疗方法。研究方法选取符合此病诊断标准的60例病例,采用随机对照临床实验设计,分为治疗组、对照组,每组30例。治疗组予以健脾疏肝汤内服,每日一剂,分早晚温服,对照组予以逍遥散内服,每日一剂,分早晚温服。根据患者实际情况,观察并记录两组患者治疗前、后的焦虑倾向、SF量表及治疗前、后的中医症状量化积分,并做统计学处理分析结果。研究结果1.治疗组与对照组治疗前随机因素(性别、年龄、病程)无明显差异(P0.05)。2.汉密尔顿焦虑量表(HAMA):两组患者中,轻度、中度焦虑的患者所占比例较大,其中治疗组轻中度焦虑患者为80%,对照组轻中度焦虑患者为86.6%。两组P0.05,具有统计学意义。2.SF--36量表:两组治疗前比较,无显著性差异(P0.05)。治疗组前后、对照组前后的八个生理维度比较有统计学差异(P0.05)。两组治疗后比较,其中精力组、社会功能组P0.05,无统计学差异;生理职能组、躯体疼痛组、精神健康、一般健康状况组、情感职能组,P均小于0.05,均具有统计学差异。3.中医症候积分:两组患者治疗前比较,P0.05,故两组患者治疗前不存在统计学差异;两组患者治疗后半月、治疗后1月组间比较,P0.05,具有统计学差异;两组患者治疗前与治疗后半月组内比较,两组P0.01(P=0.000),治疗前后存在显著差异。治疗组治疗后半月与治疗后1月,P0.05有统计学差异,对照组治疗后半月与治疗后1月,P0.05,不具有统计学差异。4.两组患者治疗期间均未见明显毒副作用、不良反应及过敏现象。结论1.罹患肛门直肠神经官能症的患者,很大一部分伴有焦虑倾向,此病的发生与精神活动息息相关。2.对于肝郁脾虚证的肛门直肠神经官能症的患者,健脾疏肝汤能有效改善临床症状,提高患者生活质量,比逍遥散临床疗效更明显。
[Abstract]:Objective to observe the clinical efficacy of Jianpi Shugan decoction in the treatment of anorectal neurosis (liver depression and spleen deficiency syndrome), and to evaluate the effectiveness of Jianpi Shugan decoction in the treatment of this disease. To provide a feasible and effective treatment for this disease. Methods Sixty patients who met the diagnostic criteria were divided into treatment group and control group with 30 cases in each group. The treatment group was taken orally with Jianpi Shugan decoction, one dose per day, divided into morning and evening warm clothes, while the control group was given Xiaoyao Powder, one dose daily, one daily, and one morning and evening warm. According to the actual situation of the patients, we observed and recorded the anxiety tendency of the two groups before and after treatment with SF scale and the quantitative scores of TCM symptoms before and after treatment, and made statistical analysis results. Results 1. There was no significant difference in random factors (sex, age, course of disease) between the treatment group and the control group before treatment (P 0.05). Hamilton anxiety scale (Hamilton anxiety scale): the proportion of mild and moderate anxiety was higher in the two groups, 80 in the treatment group and 86.6 in the control group. 2. SF-36 scale: there was no significant difference before treatment between the two groups (P 0.05). Before and after the treatment group, the control group before and after the comparison of the eight physiological dimensions there was a statistical difference (P 0.05). After treatment, there was no significant difference between the two groups (P 0.05), physical function group, somatic pain group, mental health group, general health group, affective function group, P < 0.05, with statistical difference. TCM symptom score: two groups of patients before treatment compared with P0.05, so there is no statistical difference between the two groups before treatment, two groups of patients after treatment half a month, one month after treatment, there is a statistical difference between the two groups. There was a significant difference between the two groups before and after treatment. There was significant difference in the treatment group between the latter half month and the first month after treatment (P0.05), while in the control group there was no statistical difference between the latter half month and one month after treatment (P0.05). 4. There were no obvious side effects, side effects and allergies in both groups. Conclusion 1. A large proportion of patients with anorectal neurosis are associated with anxiety, which is closely related to mental activity. For patients with anorectal neurosis due to liver stagnation and spleen deficiency, Jianpi Shugan decoction can effectively improve clinical symptoms and improve the quality of life of patients, which is more effective than Xiaoyao Powder.
【学位授予单位】：湖南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R266

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