加味六味地黄汤联合八白散治疗肝肾不足型黄褐斑的临床观察

发布时间：2018-05-06 23:28

本文选题：加味六味地黄汤 + 八白散　；参考：《天津中医药》2017年03期

【摘要】：[目的]评价加味六味地黄汤联合八白散治疗肝肾不足型黄褐斑的临床疗效。[方法]采用随机数字表法将64例患者随机分为两组,即治疗组和对照组。治疗组予以加味六味地黄汤煎服,同时配合八白散外用治疗。对照组采用维生素C、维生素E口服及3%氢醒霜外用治疗。疗程12周,两组治疗前后进行黄褐斑面积和严重程度指数(MASI)评分及中医证候观察,评价临床疗效。[结果]两组治疗12周后MASI评分均降低,但治疗组MASI评分降低更明显,两组治疗前后MASI评分差值相比具有统计学差异(P0.05);治疗组有效率为89.6%,对照组有效率为66.7%,两组间有效率比较具有统计学差异(P0.05);治疗12周后,治疗组中医证候评分明显降低,与治疗前相比差异具有统计学意义(P0.05),对照组治疗前后中医证候评分无明显变化,差异无统计学意义(P0.05)。[结论]加味六味地黄汤联合八白散治疗肝肾不足型黄褐斑疗效满意。
[Abstract]:[objective] to evaluate the clinical effect of modified Liuwei Dihuang decoction combined with Babai Powder in the treatment of chloasma with deficiency of liver and kidney. Methods 64 patients were randomly divided into two groups: treatment group and control group. The treatment group was treated with decoction of Liuwei Dihuang decoction and Babai Powder for external use. The control group was treated with vitamin C, vitamin E orally and 3% hydrogen waking cream. After 12 weeks of treatment, the area and severity index of chloasma were evaluated by MASI and TCM syndromes before and after treatment. [results] after 12 weeks of treatment, the MASI scores in both groups were decreased, but the MASI scores in the treatment group were significantly lower than those in the control group. The difference of MASI score between the two groups before and after treatment was statistically different (P 0.05), the effective rate of the treatment group was 89.6 and the effective rate of the control group was 66.7, the difference between the two groups was statistically significant (P 0.05), after 12 weeks of treatment, the TCM syndrome score of the treatment group was significantly decreased. Compared with before treatment, the difference was statistically significant (P 0.05), while that of control group had no significant change before and after treatment, and the difference was not statistically significant (P 0.05). [conclusion] the curative effect of modified Liuwei Dihuang decoction combined with Babai Powder in treating chloasma with deficiency of liver and kidney is satisfactory.
【作者单位】：南京奇致整形美容医院皮肤科;
【分类号】：R275.9

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