龙胆泻肝汤治疗带状疱疹伴抑郁的疗效研究

发布时间：2018-05-07 16:41

本文选题：带状疱疹 + 抑郁症　；参考：《中国现代医学杂志》2017年14期

【摘要】：目的分析龙胆泻肝汤加减治疗对带状疱疹伴抑郁患者的疼痛程度、心理状态及免疫功能的影响。方法将86例带状疱疹伴抑郁患者纳入研究,按照随机数表法分为观察组和对照组,各43例。对照组患者接受常规西医治疗,观察组患者接受西医结合龙胆泻肝汤加减治疗,对比两组患者的疼痛程度、心理状态及免疫功能。结果观察组治疗后血清P物质、神经生长因子、前列腺素E2、白介素6水平,以及焦虑自评量表、抑郁自评量表评分与对照组比较,差异有统计学意义(P0.05),观察组低于对照组;观察组的CD3~+、CD4~+、CD8~+、CD4~+/CD8~+、自然杀伤细胞(NK)与对照组比较,差异有统计学意义(P0.05),观察组的CD3~+、CD4~+、CD4~+/CD8~+、NK高于对照组患者,CD8~+低于对照组患者。结论龙胆泻肝汤加减治疗可促进带状疱疹伴抑郁患者的病情恢复,在强化患者免疫功能方面也有积极作用。
[Abstract]:Objective to analyze the effect of addition and subtraction of long gentian Xie Gan Tang on the degree of pain, mental state and immune function of patients with herpes zoster with depression. Methods 86 cases of herpes zoster with depression were included in the study. According to the random number table method, 43 cases were divided into the observation group and the control group. The patients in the control group received conventional western medicine and the observation group received western medicine. The pain degree, mental state and immune function of the two groups were compared with the treatment of long gentian diarrhea and liver soup. Results after treatment, the serum P, nerve growth factor, prostaglandin E2, interleukin 6, and the self rating anxiety scale of the observation group were compared with the control group, the difference was statistically significant (P0.05), the observation group was statistically significant (P0.05). The CD3~+, CD4~+, CD8~+, CD4~+/CD8~+, and natural killer cells (NK) in the observation group were compared with the control group, the difference was statistically significant (P0.05). The CD3~+, CD4~+, CD4~+/CD8~+, NK of the observation group were higher than those of the control group, and CD8~+ was lower than the control group. Conclusion gentian Xie Gan Decoction can promote the recovery of patients with herpes zoster with depression. It also plays a positive role in strengthening the immune function of patients.

【作者单位】：河南省郑州人民医院医务部;
【分类号】：R275.9;R277.7

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