清疱饮治疗掌跖脓疱病的临床疗效观察

发布时间：2018-05-07 18:28

本文选题：清疱饮 + 掌跖脓疱病　；参考：《黑龙江中医药大学》2016年硕士论文

【摘要】：目的：观察中药自拟方“清疱饮”治疗湿热蕴结型掌跖脓疱病的临床疗效。方法：将76例掌跖脓疱病患者按MATLAB软件随机分成两组：治疗组(中药汤剂“清疱饮”)和对照组(雷公藤多苷片),每组各38例。在治疗过程中共有3例脱落,两组实际完成的病例数分别是37和36例。治疗组给予自拟中药“清疱饮”,并由黑龙江中医药大学附属第二医院中药煎药室制备,每剂煎取药汁300ml。早晚饭后半小时各温服150ml。对照组给予雷公藤多苷片口服,10mg/次,日3次饭后服用。总疗程均为8周,每周复诊1次,分别于治疗前即0周、治疗第2周末、第4周末和第8周末进行详细记录,记录内容包括患者主症(皮损面积及严重程度)和次症(大小便、口渴口苦及舌象)情况,并评分。结果：治疗组和对照组治疗本病湿热蕴结型均有疗效。但在主症治疗上,前者72.97%总有效,后者47.22%总有效(P0.05),前者在本病主症治疗上优于后者,并发现在脓疱、鳞屑上表现更加明显；在次症治疗上,前者89.19%总有效,后者50.00%总有效(P0.05),说明在改善本病次症上前者比后者更优秀,尤其表现在口苦、舌质和舌苔三方面。结论：1.“清疱饮”是治疗湿热蕴结型掌跖脓疱病的有效方剂。2.“清泡饮”治疗湿热蕴结型掌跖脓疱病的临床疗效优于“雷公藤多苷片”。
[Abstract]:Objective: to observe the clinical effect of Qingbingyin, a traditional Chinese medicine, on palmoplantar pustulosis with dampness and heat accumulation. Methods: 76 patients with palmoplantar pustulosis were randomly divided into two groups according to MATLAB software: treatment group (traditional Chinese medicine decoction "Qingbingyin") and control group (Tripterygium wilfordii polyglycoside tablets, 38 cases in each group). In the course of treatment, 3 cases fell out, and 37 cases and 36 cases were completed in the two groups, respectively. The treatment group was given "Qingbou drink", which was prepared by the decoction Room of the second affiliated Hospital of Heilongjiang University of traditional Chinese Medicine. Take 150 ml each half an hour after dinner in the morning and evening. The control group was given tripterygium wilfordii polyglycosides 10 mg / time, 3 times a day after meals. The total course of treatment was 8 weeks, and the patients were reviewed once a week, respectively, at the end of the 2nd, 4th and 8th weeks before treatment. The contents of the records included the patients' main symptoms (area and severity of skin lesions) and secondary diseases (defecation and urination). Thirst, bitter mouth and tongue) condition, and score. Results: both the treatment group and the control group were effective in the treatment of dampness and heat accumulation. However, the former was effective in 72.97% of the patients and the latter 47.22% in the treatment of the disease. The former was superior to the latter in the treatment of the disease, and it was found that the former was more effective in the treatment of pustules and scales, and 89.19% in the treatment of the secondary disease. The latter was 50.00% effective, indicating that the former was better than the latter in improving the secondary symptoms of the disease, especially in the three aspects of bitter mouth, tongue quality and tongue coating. Conclusion 1. Qingbingyin is an effective prescription for the treatment of dampness and heat accumulation type palmoplantar pustulosis. Qingbaoyin is superior to Tripterygium wilfordii polyglycoside in treating palmoplantar pustulosis with dampness and heat accumulation.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9

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