火针对多囊卵巢综合征性激素水平影响的临床研究

发布时间：2018-05-09 21:37

本文选题：火针疗法 + PCOS　；参考：《广州中医药大学》2016年硕士论文

【摘要】：目的：本研究旨在比较“火针疗法”和常规针刺治疗多囊卵巢综合征(PCOS)患者的临床疗效,通过观察患者治疗前后性激素水平、中医症状评分的改变情况,对“火针疗法”改善PCOS性激素水平作出客观评价,为临床治疗PCOS提供一种有效的、副作用少并且对远期并发症起到良好预防作用的治疗方法奠定理论基础,为该病的临床研究提供一种安全、可靠、创新的针灸治疗模式。方法：将符合纳入标准的60例PCOS患者随机分成治疗组(火针组)和对照组(常规针刺组),治疗组采用火针治疗,对照组采用常规针刺治疗,隔天治疗1次,每次持续30分钟,10次为一个疗程。分别在治疗前及治疗后月经期第3天抽血测定性激素水平(卵泡刺激素FSH、促黄体生成激素LH、睾酮T)水平,并用中医症状量表评分进行评价。3个疗程后,比较两组患者性激素水平和中医症状量表评分改善情况,收集数据进行统计分析。结果：1、两组患者治疗前经t检验具有可比性(P＞0.05)。治疗3个疗程后,火针组30例患者中痊愈2例,有效24例,无效4例,总有效率为86.7%；常规针刺组30例患者中痊愈0例,有效15例,无效15例,总有效率为50%。两组数据经秩和检验,P＜0.05,两组间疗效有明显差异。2、两组患者的中医症状评分量表在治疗前经t检验具有可比性(P＞0.05)。治疗3个疗程后,两组数据经t检验有显著性差异(P＜0.05)；两组自身前后对比经t检验亦具有显著性差异(P＜0.05)。3、两组患者的LH在治疗前经t检验具有可比性(P＞0.05)。治疗3个疗程后,两组数据经t检验有显著性差异(P＜0.05)；两组自身前后对比经t检验亦具有显著性差异(P0.05)。两组患者的FSH在治疗前经t检验具有可比性(P＞0.05)。治疗3个疗程后,两组数据经t检验无显著性差异(P＞0.05)。火针组自身前后经秩和检验具有显著性差异(P＜0.05)；常规针刺组自身前后经t检验具有显著性差异(P＜0.05)。两组患者的LH／FSH值在治疗前经t检验具有可比性(P＞0.05)。治疗3个疗程后,两组数据经t检验有显著性差异(P＜0.05)；火针组自身前后经t检验有显著性差异(P＜0.05)；常规针刺组自身前后经秩和检验具有显著性差异(P＜0.05)。两组患者的T在治疗前经t检验具有可比性(P＞0.05)。治疗3个疗程后,两组数据经t检验有显著性差异(P＜0.05)；火针组自身前后经秩和检验有显著性差异(p＜0.05)；常规针刺组自身前后经t检验具有显著性差异(P＜0.05)。结论：火针疗法能改善PCOS患者性激素水平、中医症状量表评分,其疗效与常规针刺相比较,更有优势。
[Abstract]:Objective: the purpose of this study was to compare the clinical efficacy of "fire acupuncture" and conventional acupuncture in the treatment of polycystic ovary syndrome (PCOS), and to observe the changes of sex hormone levels and TCM symptom scores before and after treatment. The objective evaluation of "fire needle therapy" to improve the level of sex hormone in PCOS provides a theoretical basis for clinical treatment of PCOS with less side effects and good prevention of long-term complications. To provide a safe, reliable and innovative acupuncture and moxibustion treatment model for the clinical study of the disease. Methods: sixty patients with PCOS were randomly divided into treatment group (fire acupuncture group) and control group (routine acupuncture group). The treatment group was treated with fire acupuncture, the control group was treated with conventional acupuncture, and the control group was treated once every other day. Each time lasted 30 minutes, 10 times as a course of treatment. The levels of sex hormone (follicle stimulating hormone FSH, luteinizing hormone LH, testosterone T) were measured before and after treatment on the 3rd day of menstrual period. The sex hormone level and TCM symptom scale scores were compared between the two groups, and the data were collected for statistical analysis. Results the two groups had comparable t test before treatment (P > 0.05). After 3 courses of treatment, 2 cases were cured, 24 cases were effective, 4 cases were ineffective, the total effective rate was 86.7% in the fire acupuncture group, and 0 cases were cured, 15 cases were effective, 15 cases were ineffective, and the total effective rate was 50% in the routine acupuncture group. The data of the two groups were tested by rank sum test (P < 0.05), and the curative effect was significantly different between the two groups (P < 0.05). The TCM symptom score scale of the two groups was comparable before treatment (P > 0.05). After three courses of treatment, there was significant difference between the two groups by t test (P < 0.05), and there was significant difference between the two groups by t test (P < 0.05). The LH of the two groups was comparable before and after treatment (P > 0.05). After three courses of treatment, there was significant difference between the two groups by t test (P < 0.05), and there was also significant difference between the two groups before and after treatment by t test (P 0.05). The FSH of the two groups was comparable with t test before treatment (P > 0.05). After 3 courses of treatment, there was no significant difference between the two groups by t test (P > 0.05). There was significant difference between fire acupuncture group and routine acupuncture group by rank sum test (P < 0.05) and t test before and after conventional acupuncture group (P < 0.05). The LH/FSH values of the two groups were comparable by t test before treatment (P > 0.05). After three courses of treatment, there was significant difference between the two groups by t test (P < 0.05), fire needle group (P < 0.05) before and after fire acupuncture, and routine acupuncture group (P < 0.05) by rank sum test. The T of the two groups was comparable before treatment (P > 0.05). After 3 courses of treatment, there was significant difference between the two groups by t test (P < 0 05), fire needle group (P < 0 05) by rank sum test, and routine acupuncture group (P < 0 05). Conclusion: fire acupuncture therapy can improve the level of sex hormone, TCM symptom scale, and the curative effect compared with routine acupuncture in patients with PCOS.
【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.3

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