扶正泄浊保肾汤治疗慢性肾功能衰竭患者的临床疗效及机制分析

发布时间：2018-05-11 15:22

本文选题：扶正泄浊保肾汤 + 慢性肾功能衰竭　；参考：《中药药理与临床》2017年01期

【摘要】：目的:探讨扶正泄浊保肾汤对慢性肾功能衰竭患者的治疗效果。方法:回顾性分析2014年6月~2016年6月在我院接受治疗的慢性肾功能衰竭患者的临床资料。根据其治疗方式分为对照组和观察组,对照组给予利尿、调节电解质等常规西药治疗,观察组在此基础上给予扶正泄浊保肾汤治疗,两组患者均接受3个月的治疗。观察两组的疗效,比较两组治疗前后促红细胞生成素(EPO)、甲状旁腺激素(PTH)水平、肾功能和生活质量的差异。结果:观察组治疗的有效率为97.8%,明显高于对照组;两组患者治疗前EFO和PTH水平无差别,治疗后,观察组的EFO水平明显高于对照组,PTH水平明显低于对照组;两组患者治疗前肾功能指标无差别,治疗后,观察组的血尿素氮(BUN)、血清肌酐(Scr)、血尿素和血尿酸水平均明显低于对照组;两组患者治疗前生活质量无差别,治疗后,观察组的生活质量得分明显高于对照组。结论:扶正泄浊保肾汤对慢性肾功能衰竭患者有较好的治疗效果,可明显改善患者的激素水平,提高患者的生活质量。
[Abstract]:Objective: To explore the therapeutic effect of Fuzheng Zhuo Bao Shen Decoction on patients with chronic renal failure. Methods: a retrospective analysis of the clinical data of patients with chronic renal failure treated in our hospital in June, June 2014 ~2016, was divided into the control group and the observation group, the control group was treated with diuretic, regulating electrolyte and other conventional western medicine treatment. On this basis, the observation group was given the treatment of Fuzheng Zhuozhuo Bao Shen decoction, the two groups were treated for 3 months. Observe the curative effect of the two groups, compare the difference between the erythropoietin (EPO), the parathyroid hormone (PTH) level, the renal function and the quality of life before and after the treatment of the two groups. There was no difference in the level of EFO and PTH before treatment in the two groups. After treatment, the level of EFO in the observation group was significantly higher than that of the control group, and the level of PTH was significantly lower than that of the control group. There was no difference between the two groups before treatment. After treatment, the blood urea nitrogen (BUN), serum creatinine (Scr), blood urea and uric acid level were significantly lower in the observation group than in the control group; the two groups of patients were significantly lower than the control group. There was no difference in quality of life before treatment. After treatment, the quality of life of the observation group was significantly higher than that of the control group. Conclusion: Fuzheng Zhuozhuo Bao Shen decoction has a better therapeutic effect on patients with chronic renal failure. It can obviously improve the level of hormone and improve the quality of life of the patients.

【作者单位】：河南大学淮河医院;
【基金】：开封市科技发展计划项目,项目编号:1504015
【分类号】：R277.5

【参考文献】