“祛瘀生新”疗法治疗不同疼痛性质的带状疱疹后神经痛的临床疗效观察

发布时间：2018-05-11 15:46

本文选题：“祛瘀生新”疗法 + 带状疱疹后神经痛　；参考：《南京中医药大学》2016年硕士论文

【摘要】：目的：评价“祛瘀生新”疗法对带状疱疹后神经痛患者疼痛及生活质量的改善情况,探讨此疗法对不同疼痛性质PHN疗效的差异性及时效性。方法：将符合纳入标准的40例PHN患者随机分为治疗组、对照组,每组20例,设立A组为治疗组,采用“祛瘀生新”疗法；B组为药物对照组,采用口服加巴喷丁的治疗。治疗周期为3周,分别于治疗后第1、2、3周后观察疗效。观察治疗前后三组患者视觉疼痛模拟量表(VAS)、McGill疼痛积分表、阿森斯失眠量表(AIS)的评定结果,并根据评价标准对疗效进行评估。结果：1.两组总有效率分别是95%和85%,比较具有显著差异(P0.05),A组优于B组。2.两组患者治疗3周后的VAS积分、AIS的比较具有显著性差异(P0.05),A组优于B组。两组患者治疗第1周的VAS评分下降值比较,P0.05,两组之间有显著性差异,A组在治疗第一周时对疼痛的改善程度优于B组。3.两组患者治疗前后McGill计分比较,P0.01,均有显著性差异,两组治疗后McGill计分和两组治疗前后差值比较,P0.05,差异均有统计学意义。A组患者刺痛、热灼痛、触痛、跳痛、牵扯痛的McGill计分与B组相比,具有显著差异(P0.05),其中对触痛的改善效果最为明显。B组患者刀割痛、撕裂痛的McGill计分与A组相比,具有显著差异(P0.05)。结论：1.“祛瘀生新”疗法能够有效改善PHN患者疼痛程度及睡眠质量2.“祛瘀生新”疗法治疗PHN的止痛起效速度明显优于口服加巴喷丁,起效时间更短；3.“祛瘀生新”疗法对于触痛、刺痛、热灼痛、牵扯痛、跳痛的改善程度优于口服加巴喷丁,且对触痛的改善程度最为显著,口服加巴喷丁疗对刀割样痛、撕裂样痛的改善效果更好。
[Abstract]:Objective: to evaluate the improvement of pain and quality of life in patients with post herpes zoster neuralgia treated with Quyu Shengxin (QXT), and to explore the difference and time effect of this therapy in treating PHN with different pain. Methods: forty patients with PHN were randomly divided into treatment group (n = 20) and control group (n = 20). Group A was set up as treatment group, group B was treated with "Quyu Shengxin" as drug control group, and treated by oral administration of gabapentin. The treatment period was 3 weeks and the curative effect was observed 3 weeks after treatment. The evaluation results of visual pain analogue scale (VASA) McGill's pain score scale (AIS) and AIS scale before and after treatment were observed and the curative effect was evaluated according to the evaluation criteria. The result is 1: 1. The total effective rates of the two groups were 95% and 85%, respectively. There was a significant difference in VAS scores between the two groups after 3 weeks of treatment. Group A was better than group B. There was significant difference between the two groups in the decrease of VAS score in the first week of treatment (P 0.05). The improvement of pain in group A was better than that in group B at the first week of treatment (P 0.05). There was significant difference in McGill score between the two groups before and after treatment (P 0.01). The difference between the two groups in McGill score and the difference between the two groups before and after treatment was significant (P 0.05). The difference was statistically significant in group A. the patients in group A had stinging pain, heat burning pain, tenderness and jumping pain. There was significant difference in McGill score between group B and group B. among them, the effect of improving tenderness was the most obvious. The McGill score of group B was significantly different from that of group A (P 0.05). Conclusion 1. Quyu Shengxin therapy can effectively improve the pain degree and sleep quality of PHN patients. The analgesic effect of "Quyu Shengxin" therapy on PHN was significantly faster than that of oral gabapentin, and the effective time was much shorter than that of gabapentin. The improvement degree of "Quyu Shengxin" therapy for tenderness, stinging, heat burning, pulling pain and jumping pain was better than that of oral gabapentin, and the improvement degree of tenderness was the most obvious. The effect of tearing pain is better.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9

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