心脑通络液治疗冠心病早搏（气虚血瘀型）的临床观察

发布时间：2018-05-12 04:45

本文选题：心脑通络液 + 气虚血瘀　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:通过观察心脑通络液治疗冠心病早搏(气虚血瘀型)的中医证候积分及动态心电图指标,初步探讨中药复方制剂对冠心病早搏的临床疗效。方法:选择符合入组标准的42例门诊冠心病早搏患者(中医辨证为气虚血瘀型),给予服用心脑通络液治疗,每日3次,每次20ml,前后治疗4周。在治疗前和治疗后分别记录患者的中医证候积分、24h动态心电图早搏数量、平均心率及心率变异性指标数据,数据采用SPSS 19.0软件分析结果。结果:1、中医证候疗效:治疗前后中医证侯总积分比较,治疗后中医证侯总积分减小,差异具有统计学意义(P0.01);治疗后中医证侯疗效的总有效率为87.5%,其中显效者有14例(35%),有效者有21例(52.5%),无效者有5例(12.5%)。2、24h动态心电图疗效:治疗前后早搏数量比较,治疗后早搏数量减少,差异具有统计学意义(P0.01);治疗前后平均心率比较,差异无统计学意义(P0.05);治疗前后心率变异性(SDNN、SDANN、SDNNinde x、rMSSD、PNN50)比较,差异有统计学意义(P0.01)。治疗后早搏的总有效率为80.00%,其中室上性早搏、室性早搏、室上性合并室性早搏治疗的有效率分别是81.82%、75.00%、80.00%;结论:1、心脑通络液能改善冠心病早搏(气虚血瘀型)患者的中医证候。2、心脑通络液能减少冠心病早搏(气虚血瘀型)患者的早搏数量,不影响平均心率。3、心脑通络液能提高冠心病早搏(气虚血瘀型)患者的心率变异性,改善其自主神经功能。
[Abstract]:Objective: to investigate the clinical effect of traditional Chinese medicine (TCM) compound preparation on premature beats of coronary heart disease (CHD) by observing TCM syndromes integral and dynamic electrocardiogram (ECG) indexes in treating premature beats of coronary heart disease (CHD) with Xinnao Tongluo liquid (XNTL). Methods: 42 outpatients with premature beats of coronary heart disease (TCM syndrome differentiation: Qi deficiency and blood stasis type) were selected and treated with Xinnao Tongluo liquid 3 times a day, 20 ml each time for 4 weeks before and after treatment. Before and after treatment, the scores of TCM syndromes and 24 h ambulatory ECG premature beats, mean heart rate and heart rate variability were recorded respectively. The data were analyzed by SPSS 19.0 software. Results 1. Curative effect of TCM syndrome: the total score of TCM syndrome before and after treatment was compared, and after treatment, the total score of TCM syndromes decreased. The difference was statistically significant (P 0.01), the total effective rate of TCM syndromes after treatment was 87.5%, of which 14 cases were effective, 21 cases were effective and 52.5 cases were effective, 5 cases were ineffective, and 5 cases had 24 hours ambulatory electrocardiogram effect: comparison of the number of premature beats before and after treatment. After treatment, the number of premature beats decreased, the difference was statistically significant (P 0.01), the mean heart rate before and after treatment had no significant difference (P 0.05), and the heart rate variability (SDNV) was SDNN Nine de XM MSSDPNN50 (P 0.01). The total effective rate of premature beats after treatment was 80.00g, in which supraventricular premature beats, ventricular premature beats, The effective rates of supraventricular and ventricular premature beats were 81.82 and 75.00, respectively. Conclusion: 1, Xinnao Tongluo liquid can improve TCM syndromes of patients with premature coronary heart disease (Qi deficiency and blood stasis type), and Xinnao Tongluo liquid can reduce premature beats of coronary heart disease (Qi deficiency and blood stasis type). The number of premature beats in patients, Without affecting the mean heart rate, Xinnao Tongluo liquid could improve the heart rate variability and improve the autonomic nervous function of patients with premature beats of coronary heart disease (qi deficiency and blood stasis type).
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

【参考文献】