中医综合外治法冶疗膝骨性关节炎的临床疗效观察

发布时间：2018-05-12 14:31

本文选题：中医综合外治法 + 临床疗效　；参考：《西南医科大学》2016年硕士论文

【摘要】：目的:系统观察中医综合外治法即穴位麝香祛痛搽剂离子导入疗法+祛风骨痛巴布膏贴敷疗法治疗膝骨性关节炎的临床疗效,以期探索疗效肯定、行业公认、操作简便、易于推广的治疗膝骨性关节炎的中医外治综合方案。方法:本试验采用单中心随机对照研究方法,所有病例均来自四川省骨科医院康复科。按照随机分组原则,将其所收集的102例相关患者分为两组,即治疗组52例,对照组50例。治疗组采用由“穴位麝香祛痛搽剂离子导入疗法+祛风骨痛巴布膏贴敷疗法”组成的中医外治综合方案治疗,对照组采用由“扶他林乳胶剂导入疗法+酮洛芬贴膜剂贴敷疗法”组成的标准西医外治方案治疗,两组受试者每日治疗一次,连续7天为一个疗程,共治疗2个疗程(2周)。观察两组患者治疗前后疼痛(视觉模拟评分即VAS)评分及加拿大骨性关节炎指数(WOMAC)各项评分的变化情况,系统评价中医综合外治法治疗膝骨性关节炎的临床疗效。结果:1.两组基线比较:治疗前对两组患者性别、年龄、病情、疼痛程度、病程等基线情况进行组间比较,结果均无统计学意义(P0.05),提示组间具有可比性。2.两组疼痛(VAS)评分比较:两组治疗方法均能明显降低患者的VAS疼痛评分(P0.05),且治疗组优于对照组(P0.05)。3.两组加拿大骨性关节炎指数(WOMAC)各项评分比较:(1)两组关节功能评分比较:两组关节功能评分较治疗前均有降低(P0.05),治疗组略优于对照组但无统计学意义(P0.05)。(2)两组僵硬评分比较:两组僵硬评分较治疗前均有降低(P0.05),治疗组略优于对照组但无统计学意义P0.05)。(3)两组疼痛评分比较:两组疼痛评分较治疗前均有降低(P0.05),治疗组明显优于对照组且具有统计学意义(P0.05)。4.两组总体疗效比较:治疗组有效率为100%,而对照组有效率为98%,两组无显著差异(P0.05)。进一步分析两组显效率,治疗组显效率为96%明显高于对照组的80%,且差异具有统计学意义(P0.05)。5.整个治疗过程中,两组均无不良反应发生。结论:1.中医综合外治法即穴位麝香祛痛搽剂离子导入疗法+祛风骨痛巴布膏贴敷疗法治疗膝骨性关节炎有效,尤其在改善关节疼痛方面疗效显著。2.中医综合外治法即穴位麝香祛痛搽剂离子导入疗法+祛风骨痛巴布膏贴敷疗法操作简便、安全有效,具有推广应用的前景。
[Abstract]:Objective: to observe the clinical effect of treating knee osteoarthritis with comprehensive external treatment of traditional Chinese medicine (TCM), I. e., ion-introduction therapy of acupoint musk dispelling pain liniment, expelling wind and bone pain, and applying patina ointment to treat knee osteoarthritis, in order to explore the definite curative effect, trade recognition and simple operation. Easy to promote the treatment of knee osteoarthritis external treatment of Chinese medicine comprehensive plan. Methods: a single-center randomized controlled study was conducted. All cases were from the Rehabilitation Department of Sichuan Orthopaedics Hospital. According to the principle of random grouping, 102 patients were divided into two groups: treatment group (52 cases) and control group (50 cases). The treatment group was treated by external therapy of traditional Chinese medicine, which was composed of "point musk dispel pain liniment iontophoresis therapy, expelling wind and bone pain and patina plaster". The control group was treated with the standard western medicine external treatment regimen composed of "Fu Thalin Latex Introduction Therapy, ketoprofen Patch membrane Application Therapy". The two groups were treated once a day for 7 days as a course of treatment, and 2 courses of treatment were given for 2 weeks. To observe the changes of pain (visual analogue score (VAS) score) and Canadian osteoarthritis index (WOMAC) before and after treatment in two groups, and to evaluate systematically the clinical effect of comprehensive external treatment of traditional Chinese medicine on knee osteoarthritis. The result is 1: 1. Baseline comparison between the two groups: before treatment, the baseline data of gender, age, condition, pain and course of disease were compared between the two groups. The results showed that there was no significant difference between the two groups (P 0.05), indicating that there was comparability between the two groups. 2. Comparison of pain score between the two groups: the VAS pain score was significantly decreased in both groups, and the treatment group was superior to the control group. Comparison of the scores of two groups of Canadian Osteoarthritis Index (WOMAC1): the scores of joint function in both groups were lower than those before treatment (P 0.05), the treatment group was a little better than the control group, but there was no significant difference between the two groups (P 0.05). Comparison: the scores of stiffness in both groups were lower than those before treatment, and the scores in the treatment group were slightly better than those in the control group, but there was no significant difference between the two groups in terms of pain score (P 0.05): the pain score of the two groups was lower than that of the control group (P 0.05), and the treatment group was obviously better than the control group. And it has statistical significance (P 0.05. 4). Comparison of the overall curative effect between the two groups: the effective rate in the treatment group was 100 and the effective rate in the control group was 98. There was no significant difference between the two groups (P 0.05). Further analysis showed that the effective rate of the treatment group was 96% higher than that of the control group (80%), and the difference was statistically significant (P 0.05). There were no adverse reactions in both groups during the whole course of treatment. Conclusion 1. The comprehensive external treatment of traditional Chinese medicine (TCM) is effective in the treatment of knee osteoarthritis, especially in the improvement of joint pain, especially in the treatment of knee osteoarthritis, especially in the treatment of knee osteoarthritis by ion-introduction therapy of acupoint musk dispelling pain liniment. The comprehensive external treatment of traditional Chinese medicine (TCM) is the ion-introduction therapy of acupoint musk dispel pain liniment, which is simple, safe and effective, and has the prospect of popularization and application.
【学位授予单位】：西南医科大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R274.9

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