育阴制阳法治疗2型糖尿病合并高血压肝肾阴虚阳亢证的临床研究

发布时间：2018-05-12 19:13

本文选题：滋补肝肾 + 育阴制阳　；参考：《山东中医药大学》2016年硕士论文

【摘要】：目的:通过临床观察,研究育阴制阳法针对2型糖尿病合并高血压肝肾阴虚阳亢证患者,在减轻症状和体征,以及降低患者的血糖、糖化血红蛋白、血压、血脂等指标方面的效果,并在总结该病发病机理的基础上探讨该治法的作用机制。方法:选择60例符合2型糖尿病合并高血压肝肾阴虚阳亢证的患者,随机平均分为试验组和对照组,两组在饮食、运动干预方面无区别。对照组给予基础降糖降压西药治疗;试验组在给予对照组治疗方案的基础上配伍滋补肝肾,育阴制阳的中药。一疗程为8周,均观察1个疗程,治疗前后分别记录观察两组症状、体征的前后变化,以及血糖、糖化血红蛋白、血压、血脂的检验结果以及安全性。结果:治疗前两组之间的血糖、糖化血红蛋白、血压、血脂、症候总积分等各项指标经统计分析,具有可比性。治疗后两组在血糖、糖化血红蛋白、血压方面均有降低,并能改善患者的脂代谢以及症状、体征,相比较而言,试验组比对照组在疗效上更具优势。结论:运用滋补肝肾,育阴制阳法能够有效提高疗效,改善临床症状以及糖代谢、脂代谢、降低血压,且安全性高。证实了在中医整体观念、辨证论治的思想指导下的治疗方法拥有其独特的优势。
[Abstract]:Objective: to study the effect of yin-nourishing method on relieving symptoms and signs, reducing blood sugar, glycosylated hemoglobin and blood pressure in patients with type 2 diabetes mellitus complicated with hyperactivity of liver and kidney yin and yang. On the basis of summarizing the pathogenesis of the disease, the mechanism of the treatment was discussed. Methods: sixty patients with type 2 diabetes mellitus complicated with hyperactivity of liver and kidney yin deficiency and yang hyperactivity were randomly divided into two groups: experimental group and control group. There was no difference in diet and exercise intervention between the two groups. The control group was treated with basic western medicine for lowering blood pressure and blood pressure, while the experimental group was treated with traditional Chinese medicine for nourishing liver and kidney and nourishing yin and regulating yang on the basis of the treatment scheme of control group. One course of treatment was 8 weeks. The changes of symptoms, signs, blood sugar, glycosylated hemoglobin, blood pressure, blood lipids and safety were recorded before and after treatment. Results: the indexes of blood sugar, glycosylated hemoglobin, blood pressure, blood lipids, symptom total score and so on before treatment were comparable. After treatment, the blood glucose, glycosylated hemoglobin and blood pressure of the two groups were decreased, and the lipid metabolism, symptoms and signs of the patients were improved. Compared with the control group, the treatment group had more advantages in curative effect. Conclusion: the method of nourishing liver and kidney, nourishing yin and regulating yang can effectively improve the curative effect, improve clinical symptoms, glucose metabolism, lipid metabolism, lower blood pressure, and have high safety. It has proved that the treatment method under the guidance of the whole concept of TCM and the thought of syndrome differentiation has its unique advantages.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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