祛瘀止血散鼻胃管推注对胃十二指肠溃疡大出血患者止血改善程度的评估

发布时间：2018-05-13 01:24

  本文选题：鼻胃管推注 + 祛瘀止血散　； 参考：《中国中医基础医学杂志》2017年08期

【摘要】：目的:对胃十二指肠溃疡大出血患者鼻胃管推注祛瘀止血散的止血改善程度进行评估。方法:选取2014年6月至2016年2月胃十二指肠溃疡大出血患者86例,按随机数字法分为观察组和对照组各43例,对照组给予奥美拉唑40 mg、对氨甲基苯甲酸注射液0.2 g、西米替丁0.2 g静脉滴注,qd。观察组在对照组治疗基础上加用祛瘀止血散鼻胃管推注,2组均治疗14 d为1个疗程,对2组患者治疗前后症状评分和实验室指标进行观察评估。结果:2组治疗后呕血、黑便等症状评分与治疗前比较均有明显降低,且观察组低于对照组,观察组治疗后血小板计数(blood platelet,PLT)显著高于对照组,便隐血(fecal occult blood)阳性率显著低于对照组;观察组治疗后经Rockall评分高危占13.95%,低危占65.12%,低危人数显著高于对照组,高危人数显著低于对照组(Uc=-3.8606),2组比较差异有统计学意义。结论:鼻胃管推注祛瘀止血散可以增强胃十二指肠溃疡大出血患者血小板聚集功能,促进创口止血愈合,明显改善患者临床症状。
[Abstract]:Objective: to evaluate the degree of hemostasis in patients with massive bleeding of gastroduodenal ulcer. Methods: 86 patients with massive bleeding of gastroduodenal ulcer from June 2014 to February 2016 were randomly divided into observation group (n = 43) and control group (n = 43). The control group was given omeprazole (40 mg), p-aminomethylbenzoic acid injection (0.2 g) and simitidine (0.2 g iv). On the basis of the treatment of the control group, the observation group was treated with removing stasis and hemostatic powder for 14 days. The symptom scores and laboratory indexes were observed and evaluated before and after treatment in both groups. Results after treatment, the scores of hematemesis, melanology and other symptoms in the observation group were significantly lower than those in the control group, and the platelet count in the observation group was significantly higher than that in the control group. The positive rate of fecal occult blood in the observation group was significantly lower than that in the control group, and the high risk rate was 13.95, the low risk was 65.12 in the observation group, and the number of the low risk was significantly higher than that in the control group, and the number of high risk was significantly lower than that in the control group, which was significantly lower than that in the control group. Conclusion: nasogastric tube injection of Quyu Zhixue Powder can enhance platelet aggregation in patients with massive bleeding of gastroduodenal ulcer, promote wound hemostasis healing, and improve the clinical symptoms of the patients.
【作者单位】： 滨州医学院附属医院;滨州市中医医院;
【分类号】：R259
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本文编号：1881032