寿胎丸合五苓散加减方治疗脾肾亏虚型早期妊娠合并中度卵巢过度刺激综合征的临床研究

发布时间：2018-05-13 06:06

本文选题：脾肾亏虚型 + 早期妊娠合并中度卵巢过度刺激综合征　；参考：《山东中医药大学》2016年硕士论文

【摘要】：目的:通过临床研究,观察中药治疗脾肾亏虚型早期妊娠合并中度卵巢过度刺激综合征的临床疗效,并根据中医药理论探讨卵巢过度刺激综合征(OHSS)的病因病机,为更好的治疗卵巢过度刺激综合征提供更多依据。方法:临床选取26例符合纳入标准的脾肾亏虚型早期妊娠合并中度卵巢过度刺激综合征患者,并随机分为治疗组和对照组各13例。对照组给予低分子右旋糖酐氨基酸注射液及羟乙基淀粉200/0.5氯化钠注射液治疗;治疗组在对照组治疗的基础上联合寿胎丸合五苓散加减方治疗,通过临床试验研究,比较两组在维持正常妊娠并改善临床症状及体征等方面的治疗效果。结果:治疗组与对照组经规范治疗后在降低中医证候学积分,增加尿量,减小腹围及体质量指数,减小卵巢直径及盆腔积液量等方面具有显著疗效,通过治疗前后数据分析发现,治疗组在改善上述症状方面优于对照组,而且在整个研究过程中未出现安全指标异常及其他不良症状,因此说明寿胎丸合五苓散在治疗早期妊娠合并中度OHSS有良好的疗效。结论:中药寿胎丸合五苓散加减方对治疗早期妊娠合并中度OHSS方面有显著疗效,较对照组单纯使用西药治疗有明显效果,因此可以在临床上采用此方法治疗该类疾病。
[Abstract]:Objective: to observe the clinical effect of traditional Chinese medicine in treating early pregnancy with moderate ovarian hyperstimulation syndrome with deficiency of spleen and kidney, and to explore the etiology and pathogenesis of ovarian hyperstimulation syndrome (OHSS) according to the theory of traditional Chinese medicine. To provide more evidence for better treatment of ovarian hyperstimulation syndrome. Methods: 26 cases of early pregnancy with moderate ovarian hyperstimulation syndrome with deficiency of spleen and kidney were selected and randomly divided into treatment group and control group. The control group was treated with low molecular weight dextran amino acid injection and hydroxyethyl starch 200 / 0.5 sodium chloride injection. To compare the therapeutic effects of the two groups in maintaining normal pregnancy and improving clinical symptoms and signs. Results: after standardized treatment, the treatment group and the control group had remarkable curative effects in reducing TCM syndromes score, increasing urine volume, decreasing abdominal circumference and body mass index, reducing ovarian diameter and pelvic effusion, etc. Through the analysis of data before and after treatment, it was found that the treatment group was superior to the control group in improving the above symptoms, and there was no abnormal safety index and other adverse symptoms in the whole course of the study. Therefore, Shou-Tye Pill combined with Wuling Powder has a good curative effect on early pregnancy with moderate OHSS. Conclusion: Shou-Tye Pill combined with Wuling Powder has significant curative effect on the treatment of moderate OHSS in early pregnancy, which is more effective than that in the control group, so it can be used in clinical treatment of this kind of disease.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.9

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