平消癃清方治疗脾肾亏虚型糖尿病神经源性膀胱的临床疗效观察

发布时间：2018-05-13 17:35

本文选题：平消癃清方 + 糖尿病神经源性膀胱　；参考：《新疆医科大学》2017年硕士论文

【摘要】：目的:观察平消癃清方治疗糖尿病神经源性膀胱(中医辨证为:脾肾亏虚型)的临床疗效。方法:将符合标准的64例患者按照随机对照试验原则分为治疗组、对照组,每组各32例。对照组给予基础治疗,即控制血糖,指导患者排尿,并给予甲钴胺注射液0.5mg/次,隔一日一次肌肉注射治疗。治疗组给予基础治疗联合口服平消癃清方,200ml/次,2次/天,统一由我院制剂室代煎并发放给受试者。治疗6周后,对两组治疗前后患者主要中医症状、膀胱残余尿量、尿流率、FBG、2hPBG、HbA1C等指标进行统计分析。结果:与对照组相比,平消癃清方能明显改善脾肾亏虚型糖尿病神经源性膀胱患者的临床症状(P0.05),有效减少膀胱残余尿量(P0.01),明显增加DNB患者的最大尿流率(P0.01),而对FBG、2hPBG、HbA1C无明显作用(P0.05)。结论:(1)平消癃清方治疗脾肾亏虚型糖尿病神经源性膀胱患者临床疗效确切,能有效改善患者临床症状、增加最大尿流率、减少膀胱残余尿量,改善排尿功能障碍,并且安全经济,值得在临床上进行推广。(2)通过对治疗前后各项实验室指标进行分析表明中西医结合治疗脾肾亏虚型糖尿病神经源性膀胱疗效优于单纯西医治疗。
[Abstract]:Objective: to observe the clinical effect of Pingxiaolong Qingfang on diabetic neurogenic bladder (TCM syndrome differentiation: deficiency of spleen and kidney). Methods: according to the principle of randomized controlled trial, 64 patients were divided into two groups: treatment group (n = 32) and control group (n = 32). The control group was given basic treatment, that is, controlling blood sugar, instructing patients to urinate, and giving megalobalamin injection 0.5mg/ once every other day. The treatment group was treated with basic treatment combined with oral administration of Pingxiaolong prescription 200 ml / L twice a day, which was prepared by our hospital and distributed to the subjects. After 6 weeks of treatment, the main symptoms of traditional Chinese medicine (TCM), residual urine volume of bladder and urinary flow rate (FBGG 2hPBGV HbA1C) were statistically analyzed before and after treatment. Results: compared with the control group, Pingxiaolong Qing prescription could significantly improve the clinical symptoms of neurogenic bladder patients with deficiency of spleen and kidney, reduce the residual urine volume of bladder and increase the maximum urine flow rate of patients with DNB (P0.01A), but had no significant effect on the patients with DNB 2hPBGGG HbA1C. Conclusion the clinical efficacy of Pingxiaolong prescription in treating neurogenic bladder of diabetes mellitus with deficiency of spleen and kidney is definite. It can effectively improve the clinical symptoms, increase the maximum urine flow rate, reduce the residual urinary volume of the bladder, and improve the urination dysfunction. It is safe and economical. It is worth popularizing in clinic. (2) by analyzing the laboratory indexes before and after treatment, it is shown that the curative effect of integrated traditional Chinese medicine and western medicine in treating diabetic neurogenic bladder with deficiency of spleen and kidney is better than that of western medicine alone.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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