凉血消银汤口服联合消银熏洗汤外用治疗寻常型银屑病血热证效果观察

发布时间：2018-05-15 03:32

本文选题：凉血消银汤 + 消银熏洗汤　；参考：《山东医药》2017年22期

【摘要】：目的观察凉血消银汤口服联合消银熏洗汤外用治疗寻常型银屑病血热证的效果,及其对血清血管内皮生长因子(VEGF)水平的影响。方法将120例寻常型银屑病血热证患者随机分为A、B、C组,3组均局部外用复方黄连油,A组口服凉血消银汤,B组消银熏洗汤局部外洗,C组口服凉血消银汤并用消银熏洗汤局部熏洗,2周为1个疗程,共4个疗程。治疗前后行银屑病面积与严重性指数评分评价临床疗效,观察不良反应发生情况,并检测3组血清VEGF水平。结果 A、B、C组临床疗效总有效率分别为70.0%、70.0%、97.5%,C组与A、B组比较,P均0.05。3组未发现明显不良反应。与治疗前相比,3组治疗后血清VEGF水平均低,且C组较A、B组低(P均0.05)。结论凉血消银汤口服联合消银熏洗汤外用治疗寻常型银屑病血热证效果好,其机制可能与降低患者外周血VEGF水平有关。
[Abstract]:Objective to observe the effect of Liangxue Xiaoyin decoction combined with Xiaoyin fumigation decoction on the blood fever of psoriasis vulgaris and its effect on the level of serum vascular endothelial growth factor (VEGF). Methods 120 patients with psoriasis vulgaris syndrome were randomly divided into three groups: group A and group C were treated locally with compound Coptis chinensis oil. Group A was given orally Liangxuxiaoyin decoction, group B and group C were treated with Liangxue Xiaoyin decoction and Xiaoyin fumigation decoction. Local fumigation and washing for 2 weeks as a course of treatment, There were 4 courses of treatment. The area and severity index of psoriasis before and after treatment were used to evaluate the clinical efficacy, observe the occurrence of adverse reactions, and detect the level of serum VEGF in the three groups. Results the total effective rate of clinical efficacy in group A and B was 70.0 and 70.0 respectively. There were no significant adverse reactions in group C and group A (P = 0.05.3). The levels of serum VEGF in group C were lower than those in group A and group B were lower than those in group A (P < 0.05). Conclusion the effect of Liangxue Xiaoyin decoction combined with Xiaoyin fumigation decoction on blood fever syndrome of psoriasis vulgaris is good. The mechanism may be related to the decrease of VEGF level in peripheral blood of patients with psoriasis vulgaris.
【作者单位】：山东中医药大学第一临床医学院;山东中医药大学附属医院;
【基金】：山东省中医药科技发展计划项目(2011-056)
【分类号】：R275.9

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