参黄熏洗方促进湿热下注型肛瘘术后创面愈合的临床研究

发布时间：2018-05-15 05:13

本文选题：参黄熏洗方 + 湿热下注型　；参考：《福建中医药大学》2016年硕士论文

【摘要】：目的：观察参黄熏洗方促进湿热下注型肛瘘术后创面愈合的作用。方法：按病例选择标准选择60例肛瘘患者,随机分为2组,参黄熏洗方组(治疗组)和高锰酸钾组(对照组)均为30例。治疗组自术后第2天开始用参黄熏洗方熏洗,常规换药,每日一次,14天为一个疗程；对照组自术后第2天给予高锰酸钾溶液(1：5000)熏洗,常规换药,每日一次,14天为一个疗程。分别于术后第2天、第7天、第14天记录创面疼痛、肉芽形态、分泌物情况；手术当天、术后第7天、第14天测算创面面积大小,计算创面愈合率；评估术后总体疗效；记录创面完全愈合时间。结果：1-组内比较：用药后创面疼痛、渗液及创口肉芽生长情况均有显著性差异(P0.05)；组间比较：术后第2天创面疼痛、渗液及创口肉芽生长情况均无显著性差异(P0.05)；术后第7、14天创面疼痛、创面渗液及创口肉芽生长情况均有差异显著(P0.05),治疗组优于对照组。2.创面愈合率：组内比较,用药后两组均有差异显著(P0.05)；组间比较,术后第7、14天均有显著差异(P0.05),治疗组优于对照组。3.创面愈合时间：治疗组创面愈合时间为15～28天,平均愈合时间为17.73±2.599天,对照组创面愈合时间为16-32天,平均愈合时间为20.62±3.820天,两组比较,有显著性差异(P0.05),治疗组优于对照组。4.两组治疗后症状、体征均消失,临床总疗效均为100%。两组总疗效比较差异无统计学意义。5.用药过程中两组未发现明显不良反应。结论：通过临床研究表明,参黄熏洗方具有显著清热燥湿、散结止痛等作用,能明显缓解肛瘘术后创面疼痛,减少创面分泌物、促进创面肉芽组织的生长,提高创面愈合的质量,缩短了创面愈合时间,疗效优于高锰酸钾,值得临床推广应用临床。
[Abstract]:Objective: to observe the effect of Shenhuang fumigation and washing prescription on wound healing after wet-heat injection anal fistula. Methods: sixty patients with anal fistula were randomly divided into two groups: the treatment group (30 cases) and the potassium permanganate group (30 cases). The treatment group was fumigated and washed with Shenhuang fumigation formula from the second day after operation, routine dressing was changed once a day for 14 days as a course of treatment, the control group was given potassium permanganate solution 1: 5 000) fumigation washing from the second day after operation, routine dressing change, 14 days a day as a course of treatment. The wound pain, granulation morphology and secretion were recorded on the 2nd, 7th and 14th day after operation, the size of the wound was calculated on the 7th day and the 14th day after the operation, and the rate of wound healing was calculated, and the overall curative effect was evaluated. The time of complete wound healing was recorded. Results: there were significant differences in wound pain, exudate and granulation growth between the two groups (P 0.05). There was no significant difference in the growth of granulation in exudate and wound, but there was significant difference in wound pain, wound exudation and granulation growth on day 714 after operation. The treatment group was superior to the control group (P < 0.05). Wound healing rate: there was significant difference in wound healing rate between the two groups after treatment, and there was significant difference between the two groups on the 7th day after operation (P 0.05), which was better than that in the control group (P 0.05). Wound healing time: the healing time of the treatment group was 1528 days, the average healing time was 17.73 卤2.599 days, and that of the control group was 16-32 days and the average healing time was 20.62 卤3.820 days. There was a significant difference between the two groups (P 0.05), and the treatment group was better than the control group (.4). Symptoms and signs disappeared after treatment in both groups, and the total clinical efficacy was 100. There was no significant difference in total curative effect between the two groups. No obvious adverse reactions were found in the two groups. Conclusion: the clinical study shows that Shenhuang fumigation and washing prescription has the effects of clearing heat, drying and dampness, dispersing and relieving pain, relieving pain of wound after anal fistula, reducing the secretion of wound, and promoting the growth of granulation tissue of wound. To improve the quality of wound healing and shorten wound healing time, the curative effect is better than potassium permanganate.
【学位授予单位】：福建中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R266

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