针药联合治疗高血压病（阴虚阳亢证）合并焦虑抑郁状态临床观察

发布时间：2018-05-15 12:17

本文选题：高血压病 + 焦虑抑郁状态　；参考：《长春中医药大学》2016年硕士论文

【摘要】：目的:通过4周的西医规范化治疗加中医针药联合法治疗,旨在降低血压,缓解焦虑抑郁状态,缩短治疗时间,减轻患者精神、经济负担,从而拓展对高血压病的综合中医治疗手段,为制定“双心医学”模式下的高血压病中医诊疗常规奠定基础。方法:选择西医诊断为高血压病(2级,中危险组)或以上合并焦虑抑郁状态患者60例。将患者随机分为:中医针药联合法治疗组、西药对照组,按1:1比例分配,西医对照组采用国际公认的一线降压药苯磺酸左旋氨氯地平2.5mg/次(或联合应用厄贝沙坦0.15g/次),日1次,抗焦虑抑郁药氟哌噻吨美利曲辛10.5mg/次,日1次治疗;中医针药联合法治疗组在对照组的基础上加之滋阴补肾,平肝潜阳中药免煎颗粒冲150ml,日两次口服,平肝潜阳,调和气血针刺日1次治疗。疗程4周,入组后进行一次血压值监测临床症状积分评测,SAS、SDS自评和生活质量评定表。血压监测是在治疗1周后、2周后和治疗结束后,疗程结束后再进行中医证候积分和SAS自评、SDS自评、SF-12。结果:经过临床研究验证,相对比常规治疗方案,针药联合治疗高血压(阴虚阳亢证)合并焦虑抑郁状态方面:能降低血压(P0.01),对改善焦虑抑郁、各中医症状及提高生活质量均有显著疗效(P0.05)。结论:针药联合治疗高血压病(阴虚阳亢证)合并焦虑抑郁状态临床疗效确切、安全,是一种可靠的治疗方法。
[Abstract]:Objective: to reduce blood pressure, relieve anxiety and depression, shorten the time of treatment, and relieve the mental and economic burden of patients through the standardized treatment of western medicine for 4 weeks and the combination of traditional Chinese medicine and acupuncture. In order to expand the comprehensive traditional Chinese medicine treatment of hypertension, and lay the foundation for the establishment of "double heart medicine" model of traditional Chinese medicine diagnosis and treatment of hypertension. Methods: 60 patients with anxiety and depression were selected. The patients were randomly divided into two groups: the acupuncture and medicine combined therapy group and the western medicine control group. The western medicine control group was divided into two groups according to the 1:1 ratio. The western medicine control group was treated with the internationally recognized first-line antihypertensive drug L-amlodipine 2.5mg/ (or irbesartan 0.15g/ once a day). The anti-anxiety and depressant drug droperthiothioate meritriaxine (10.5mg/) was treated once a day; the traditional Chinese medicine combined acupuncture and medicine treatment group was treated with nourishing yin and tonifying the kidney on the basis of the control group, and the Chinese medicine for calming the liver and burying yang was given to 150ml, twice a day, for calming the liver and burying the liver. Qi-Blood-Acupuncture Day 1 time treatment for tonifying Qi and Blood. After 4 weeks of treatment, the blood pressure was monitored once and the scores of clinical symptoms were evaluated with SASSDS self-evaluation and quality of life assessment. Blood pressure monitoring was performed after 1 week of treatment, 2 weeks after treatment and after the end of the course of treatment. The TCM syndromes score and SAS self-evaluation were used to evaluate SF-12. Results: compared with the routine treatment, the combination of acupuncture and medicine in the treatment of hypertension (Yin deficiency and Yang hyperactivity) combined with anxiety and depression: it can lower blood pressure and improve anxiety and depression. Each TCM symptom and improve the quality of life have remarkable curative effect (P 0.05). Conclusion: the combination of acupuncture and medicine in the treatment of hypertension (yin deficiency and yang hyperactivity) combined with anxiety and depression is effective and safe, and is a reliable treatment method.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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