益肾化浊法治疗轻度阿尔茨海默病的临床中医证候疗效
发布时间:2018-05-15 17:18
本文选题:益肾化浊法 + 阿尔茨海默病 ; 参考:《中国老年学杂志》2017年10期
【摘要】:目的观察益肾化浊法治疗轻度阿尔茨海默病(AD)的临床中医证候疗效。方法采用多中心、随机、双盲双模拟、阳性药平行对照方法,于治疗0、4、12、24 w通过中医证候量表积分评价临床疗效;治疗48 w通过长期随访量表评价远期疗效。结果中药组在改善善忘、善误、反应迟钝、腰膝酸软、倦怠思卧、头晕等症状方面优于安理申组(P0.05),起效时间更早,且远期疗效明显优于安理申组(P0.05)。结论益肾化浊法可通过改善轻度AD患者中医证候,改善其认知功能。
[Abstract]:Objective to observe the clinical effect of tonifying kidney and removing turbid in treating mild Alzheimer's disease (AD). Methods A multicenter, randomized, double-blind, double-blind and parallel control method was used to evaluate the clinical efficacy at 1224 weeks after treatment with TCM syndrome scale and 48 weeks after treatment with long-term follow-up scale. Results the traditional Chinese medicine group was superior to the Anisin group in improving the symptoms such as good memory, good mistake, slow reaction, weak waist and knee, languid thinking, dizziness and so on, and the time of onset was earlier, and the long-term effect was obviously better than that of the group of Anlisin. Conclusion the method of tonifying kidney and removing turbid can improve the cognitive function of patients with mild AD by improving their TCM syndromes.
【作者单位】: 天津中医药大学第二附属医院;
【基金】:国家重点基础研究发展计划(2010CB530405)
【分类号】:R277.7
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