益肾活血股密保方治疗早中期非创伤性股骨头坏死的临床研究
发布时间:2018-05-16 01:14
本文选题:股密保 + 非创伤性股骨头坏死 ; 参考:《南京中医药大学》2016年硕士论文
【摘要】:目的:根据回顾门诊病历的随访数据及病人主观描述,观察益肾活血中药方股密保对早中期非创伤性股骨头坏死的临床疗效。方法:按照西医纳入标准及排除标准,对2011年03月至2015年12月在苏州中医医院骨伤科科门诊就诊的23名ONFH患者的一般资料,Harris及VAS评分,影像学检查结果等进行详细的记录。最后将所得资料及数据录入电脑,建立数据库,进行统计分析。结果:1、对30例早中期ONFH患者VAS评分研究显示,服用股密保治疗后,VAS评分较治疗前有明显改善。(p0.05)2、两组比较治疗前后坏死指数评分差值研究显示,在缓解股骨头坏死进程方面,持续组疗效优于间断组。(P=0.0140.05)3、两组比较治疗前后疗效结果显示,在缓解骨髓水肿,关节积液,改善髋关节功能及缓解疼痛方面,股密保有较好疗效,但持续组疗效未见明显优势。(P0.05)4.假设:股密保治疗效果随着持续治疗时间越长,疗效越好。结论:1、股密保对患者早中期股骨头坏死患者疼痛有确切疗效。2、股密保在缓解股骨头坏死进程方面,持续用药效果明显优于间断用药。3、股密保治疗早中期股骨头坏死时,持续用药较间断用药在改善髋关节功能,减轻骨髓水肿,缓解疼痛方面没有明显治疗优势,可能是因为早中期患者体征并不明显,关节功能保留完整,治疗效果得不到体现导致。
[Abstract]:Objective: to observe the clinical effect of Yishen Huoxue traditional Chinese medicine prescription Qiumebao on nontraumatic necrosis of femoral head in early and middle period according to the follow-up data of outpatient medical records and the subjective description of patients. Methods: according to the criteria of western medicine inclusion and exclusion, the general data of 23 ONFH patients in the Department of Orthopedics and Trauma of Suzhou traditional Chinese Medicine Hospital from March 2011 to December 2015 were recorded in detail. Finally, input the data and data into the computer, set up a database, and carry out statistical analysis. Results in the study of VAS score of 30 patients with ONFH in early and middle period, the results showed that the scores of VAS were significantly improved after treatment. The difference of necrosis index between the two groups before and after treatment showed that, in the aspect of relieving the process of femoral head necrosis, there was no significant difference between the two groups in the process of osteonecrosis of the femoral head. The curative effect of the continuous group was better than that of the discontinuous group. The results of comparison between the two groups before and after treatment showed that there was a better effect in relieving bone marrow edema, joint effusion, improving hip joint function and relieving pain, but there was no obvious advantage in the treatment group. Hypothesis: the longer the duration of treatment, the better the efficacy. Conclusion the effect of femur Mibao on the pain of patients with femoral head necrosis in the early and middle period is more effective than that of the intermittent medication .Conclusion the effect of continuous medication in relieving the process of femoral head necrosis is obviously better than that of the intermittent medication of .3.When the femoral head necrosis is treated by femoral Mibao in the early and middle period, Continuous medication has no obvious advantage in improving hip joint function, alleviating bone marrow edema, and relieving pain, which may be due to the fact that the patient's physical signs are not obvious and the joint function remains intact in the early and middle period. The effect of treatment is not reflected.
【学位授予单位】:南京中医药大学
【学位级别】:硕士
【学位授予年份】:2016
【分类号】:R274.9
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