抑肝扶脾渗湿法治疗直肠癌低位前切除综合征的临床研究

发布时间：2018-05-21 18:33

本文选题：抑肝扶脾渗湿 + 痛泻要方合参苓白术散加减　；参考：《湖南中医药大学》2016年硕士论文

【摘要】：目的:研究抑肝扶脾渗湿法治疗直肠癌低位前切除综合征的临床显著疗效。方法:将满足病例纳入标准的61例直肠癌低位前切除综合征患者,随机分为口服具有抑肝扶脾渗湿功效的痛泻要方合参苓白术散加减中药颗粒(观察组)、口服西药盐酸洛哌丁胺胶囊组(对照组),两组分别服药30天后停药。两组患者经治疗后,观察各项指标:1、肛门功能指标:包括记录患者排便次数、排便时间、肛门控制力、排便功能感觉、便意;2、中医主要症状:食少纳呆、大便质地、腹胀腹痛、焦虑抑郁、嗳气频率;3、肛管直肠测压指标:肛管静息压、肛管最大收缩压、肛管最大收缩时间、直肠感觉阈值。结果:临床研究表明:经治疗30天停药后,观察组与对照组在肛门功能评价指标、中医主要症状、肛门测压指标等疗效方面比较,口服中药组(观察组)优于西医对症治疗组(对照组),差异有统计学意义(P0.05)。结论:口服具有抑肝扶脾渗湿功效中药能有效改善直肠癌低位前切除综合征患者的临床症状及体征,能畅情志、健脾胃、助运化、实大便,改善患者肛门功能,提高患者的生活质量,充分发挥了祖国国粹中医的临床魅力,体现了其辨证论治的优越性。
[Abstract]:Objective: to study the clinical effect of inhibiting liver and nourishing spleen and infiltrating dampness in the treatment of low anterior resection syndrome of rectal cancer. Methods: 61 patients with low anterior resection syndrome of rectal cancer were included in the study. They were randomly divided into two groups: Tongxie Yao Fang and Shenling Baizhu Powder with the effect of inhibiting liver and spleen dampness (observation group) and western medicine loperamine hydrochloride capsule group (control group). After treatment, the patients in the two groups were observed the indexes: 1, anus function index: including recording the defecation times, defecation time, anal control power, defecation function feeling, the main symptoms of TCM: food intake, defecation texture, abdominal distention pain, Anxiety and depression, belching frequency, anorectal manometry index: anal resting pressure, anal maximum contraction time, rectal sensory threshold. Results: the clinical study showed that after 30 days of treatment, the efficacy of the observation group and the control group in the evaluation of anal function, the main symptoms of traditional Chinese medicine and the anus manometry were compared. Oral Chinese medicine group (observation group) was better than western medicine treatment group (control group), the difference was statistically significant (P 0.05). Conclusion: Chinese herbal medicine can effectively improve the clinical symptoms and signs of patients with low anterior resection syndrome of rectal cancer, improve mood, strengthen spleen and stomach, help to transport, improve the anal function of patients with rectal cancer, and improve the anal function of patients with rectal cancer. Improve the quality of life of patients, give full play to the clinical charm of traditional Chinese medicine, reflect the superiority of syndrome differentiation.
【学位授予单位】：湖南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R273

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