血脂异常中医证型在糖尿病与非糖尿病中的分布特点及致AS指标研究

发布时间：2018-05-21 21:00

本文选题：血脂异常 + 糖尿病合并血脂异常　；参考：《福建中医药大学》2016年硕士论文

【摘要】：目的：1.探讨血脂异常证型在糖尿病与非糖尿病中的分布特点。2.探讨血脂异常中医证型与致动脉粥样硬化指标之间的关系在糖尿病与非糖尿病之间的差别。方法：从我院2014年12月至2015年11月期间在内分泌科和心血管科住院的且符合纳入排除标准的患者中,选取糖尿病合并血脂异常患者及血脂异常非糖尿病患者各200例,分别命名为糖尿病组和非糖尿病组。收集患者一般临床资料、身高、体重、血脂等指标,对数据进行统计分析。结果：1.糖尿病组的中医临床证型分布特点：气滞血瘀型(22%)痰浊阻遏型(21%)阴虚阳亢型(20%)肝肾阴虚型(19.5%)脾肾阳虚型(17.5%)。非糖尿病组的中医临床证型分布特点：痰浊阻遏型(38%)阴虚阳亢型(20%)脾肾阳虚型(18.5%)气滞血瘀型(14.5%)肝肾阴虚型(9.0%)。2.TC和LDL-C在痰浊阻遏型中阳性率均为糖尿病组少于非糖尿病组,TC、TG、AI、 TC/HDL-C在肝肾阴虚证型中的阳性率均是糖尿病组多于非糖尿病组,LDL-C/HDL-C、 HDL-C在气滞血瘀证型中阳性率均是糖尿病组多于非糖尿病组,HDL-C在阴虚阳亢证型中的阳性率是糖尿病组多于非糖尿病组。3.五种证型中,糖尿病组致AS指标的危险度多大于非糖尿病组,其中尤以LDL-C/HDL-C的水平在气滞血瘀型和痰浊阻遏型中及AI在气滞血瘀证型中的差异最为明显。糖尿病组LDL-C/HDL-C水平在证型间有差异,两两比较提示气滞血瘀型大于肝肾阴虚型。结论：1.血脂异常非糖尿病患者证型分布以痰浊阻遏型为主,糖尿病合并血脂异常者证型分布以气滞血瘀型和痰浊阻遏型为主。2.两组患者致AS指标总体以气滞血瘀和痰浊阻遏两个证型的危险性较高,糖尿病组危险性高于非糖尿病组主要表现在气滞血瘀型。3.与非糖尿病组相比,糖尿病组LDL-C/HDL-C水平在各证型组中两两比较的结果是：气滞血瘀型肝肾阴虚型,提示与血瘀证密切相关的LDL-C/HDL-C需引起重视。
[Abstract]:Purpose 1. To investigate the distribution of dyslipidemia in diabetes mellitus and non-diabetes mellitus. 2. 2. To explore the relationship between TCM syndromes of dyslipidemia and atherogenic indexes in diabetes mellitus and non-diabetes mellitus. Methods: from December 2014 to November 2015, 200 diabetic patients with dyslipidemia and 200 non-diabetic patients with dyslipidemia were selected. They were named diabetic group and non-diabetic group respectively. Collect the general clinical data, height, weight, blood lipid and other indicators, statistical analysis of the data. The result is 1: 1. The distribution characteristics of TCM clinical syndromes in the diabetic group were as follows: Qi stagnation and blood stasis type 22) phlegm turbid repressor type 21) yin deficiency and yang hyperactivity type 20) liver and kidney yin deficiency type Guang 19.5A) spleen and kidney yang deficiency type Li 17.5N. Distribution characteristics of TCM Clinical Syndrome types in Non-diabetic Group: phlegm turbidity repressor Type 38) Yin deficiency and Yang hyperactivity Syndrome: 20) spleen and Kidney Yang deficiency Type Li 18.5) Qi stagnation and Blood stasis Syndrome 14. 5) liver and Kidney Yin deficiency Type 0. 0 Wu. 2.TC and LDL-C positive rates in Diabetes Group are less than those in non-glycosyluria. The positive rates of TC/HDL-C and TC/HDL-C in the type of liver and kidney yin deficiency syndrome were higher than those in the non-diabetic group. The positive rate of HDL-C in the syndrome of qi stagnation and blood stasis was higher than that of the non-diabetic group. The positive rate of HDL-C in the type of yin deficiency and yang hyperactivity was sugar. Uropathy group was more than non-diabetic group. Among the five syndromes, the risk of as in diabetes group was higher than that in non-diabetic group, especially the level of LDL-C/HDL-C in Qi stagnation blood stasis type and phlegm turbid repressor type and AI in Qi stagnation and blood stasis type. The level of LDL-C/HDL-C in diabetic group was different between syndromes, and the comparison indicated that Qi stagnation and blood stasis type was greater than liver and kidney yin deficiency type. Conclusion 1. The distribution of syndrome type of dyslipidemia in non-diabetic patients was mainly phlegm turbid repressor type, and that in diabetic patients with dyslipidemia was mainly qi stagnation and blood stasis type and phlegm turbid repressor type. 2. The risk of blood stasis of Qi stagnation and stagnation of phlegm was higher in both groups, and the risk of diabetes group was higher than that of non-diabetic group. Compared with the non-diabetic group, the level of LDL-C/HDL-C in the diabetic group compared with each syndrome group is: Qi stagnation and blood stasis type liver and kidney yin deficiency type, suggesting that the close relationship between LDL-C/HDL-C and blood stasis syndrome should be paid attention to.
【学位授予单位】：福建中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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