益肾健脾化浊法治疗肾性贫血的临床疗效观察

发布时间：2018-05-22 16:06

本文选题：肾性贫血 + 益肾健脾化浊法　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:通过对益肾健脾化浊法治疗肾性贫血的临床观察,评定并分析益肾健脾化浊法治疗肾性贫血的临床疗效。方法:收集符合肾性贫血纳入标准60例患者,随机分成治疗组和对照组,每组各30例,两组患者均给予低盐、低脂、优质低蛋白饮食,糖尿病患者给予糖尿病饮食;在控制血压、血糖平稳的情况下,对照组给予叶酸、铁剂、rHu-EPO等常规对症治疗,治疗组在对照组治疗的基础上加服益肾健脾化浊法方药,疗程为12周。评价两组患者治疗前后的疗效及临床症状改善情况,监测治疗前后的血红蛋白(Hb),红细胞压积(HCT),红细胞计数(RBC),血清铁(SI),铁蛋白(SF)以及肌酐、尿素氮的指标。数据处理采用SPSS20.0统计学软件进行数据分析。结果:1.对照组总有效率为66.67%,治疗组总有效率为86.67%,两组疗效比较具有统计学意义(P0.05),表明治疗组优于对照组;2.治疗组和对照组在治疗后Hb,Hct,RBC,SI,SF均较治疗前升高,治疗组优于对照组,具有统计学意义(P0.05);3.治疗组在降低肌酐、尿素氮,改善中医证候积分方面优于对照组,具有统计学意义(P0.05)。结论:1.益肾健脾化浊法治疗肾性贫血,在改善肾性贫血的临床症状和体征上优于对照组;2.益肾健脾化浊法在提升血红蛋白、红细胞数目、红细胞压积、血清铁及铁蛋白的水平,降低尿素氮、血肌酐上,其作用优于对照组。
[Abstract]:Objective: to evaluate and analyze the clinical effect of tonifying kidney and invigorating spleen and removing turbidity in the treatment of renal anemia. Methods: 60 patients with renal anemia were randomly divided into treatment group and control group with 30 patients in each group. The patients in both groups were given low salt, low fat, high quality and low protein diet, and diabetic patients were given diabetes diet. Under the condition of controlling blood pressure and stable blood sugar, the control group was treated with folic acid and iron agent rHu-EPO, and the treatment group was treated with tonifying kidney and strengthening spleen and removing turbid for 12 weeks. To evaluate the curative effect and clinical symptom improvement of the two groups before and after treatment, and to monitor the indexes of HB, HCT, RBCU, SFF, creatinine and urea nitrogen before and after treatment. SPSS20.0 statistical software was used to analyze the data. The result is 1: 1. The total effective rate of the control group was 66.67 and the total effective rate of the treatment group was 86.67. The comparison between the two groups showed that the treatment group was better than the control group (P 0.05). In the treatment group and the control group, the level of HBT HcttCnrRBC+ SISF was higher than that before treatment, and the treatment group was superior to the control group, which had statistical significance (P 0.05) and the control group was significantly higher than that in the control group (P < 0.05). The treatment group was superior to the control group in reducing creatinine, urea nitrogen and improving TCM syndromes score, which had statistical significance (P 0.05). Conclusion 1. The method of tonifying kidney and invigorating spleen and removing turbid in treating renal anemia is superior to control group in improving the clinical symptoms and signs of renal anemia. The method of tonifying kidney and strengthening spleen and removing turbid could improve the levels of hemoglobin, erythrocyte, hematocrit, serum iron and ferritin, reduce urea nitrogen and serum creatinine, and its effect was superior to that of the control group.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R277.5

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