多途径治疗CKD3-4期脾肾气虚、湿浊瘀阻证型临床研究

发布时间：2018-05-24 16:43

本文选题：慢性肾脏病 + 脾肾气虚　；参考：《辽宁中医药大学》2016年硕士论文

【摘要】：目的:通过观察多途径治疗脾肾气虚、湿浊瘀阻型CKD3-4期患者的疗效情况,探讨该疗法对实验室指标及中医临床症状的影响,为进一步指导中医临床治疗实践提供依据。材料与方法:1.所有患者全部为近一年我院肾内科慢性肾脏病住院患者,依照所制定的诊断标准,纳入标准及排除标准,满足者共80例,并依据是否使用中医外治法治疗,将全部病例分为治疗组与对照组各40例,对照组患者多因个人原因拒绝接受使用中医外治法治疗。2.数据采用SPSS17.0统计软件进行分析,正态资料采用?x±s表示,采用t检验。不满足正态性时采用非参数检验,组内比较采用Wilcoxon符号秩和检验,两独立样本比较采用Mann-Whitney U检验。两组等级计数资料采用Ridit分析,以两组结果95%CI无重叠具有统计意义。结果:1.疾病疗效治疗组:显效16例,有效17例,稳定0例,无效7例,总有效率82.5%;对照组:显效5例,有效13例,稳定4例,无效18例,总有效率45%。2.中医证候疗效治疗组:痊愈0例,显效5例,有效28例,无效7例,总有效率82.5%;对照组:痊愈0例,显效1例,有效17例,无效22例,总有效率45%。结论:“一般疗法+外治法”与“一般疗法”两种方案均能一定程度上改善脾肾气虚、湿浊瘀阻型CKD患者的理化指标水平,并缓解中医临床症状。“一般疗法+外治法”较“一般疗法”治疗效果更佳,显示了多途径治疗脾肾气虚、湿浊瘀阻型慢性肾脏病的优势。
[Abstract]:Objective: to observe the effect of multi-way treatment on CKD3-4 patients with deficiency of spleen and kidney qi and dampness and stagnation, and to explore the effect of this therapy on laboratory indexes and clinical symptoms of traditional Chinese medicine (TCM), so as to provide the basis for further guiding the clinical practice of TCM. Materials and methods: 1. All the patients were all inpatients with chronic kidney disease in our hospital for nearly one year. According to the diagnostic criteria, including the criteria and exclusion criteria, 80 patients were satisfied, and according to whether or not to use the external treatment of traditional Chinese medicine, All cases were divided into treatment group and control group of 40 cases, the control group patients refused to accept the use of external Chinese medicine treatment for personal reasons. 2. The data were analyzed by SPSS17.0 software. The normal data were expressed by X 卤s and t-test were used. The nonparametric test was used when the normality was not satisfied, the Wilcoxon sign rank sum test was used in the intra-group comparison, and the Mann-Whitney U test was used in the comparison of the two independent samples. Ridit analysis was used to analyze the two groups of grade counting data, and the results of the two groups showed that 95%CI had no overlap. The result is 1: 1. In the treatment group, 16 cases were markedly effective, 17 cases were effective, 0 cases were stable, 7 cases were ineffective, and the total effective rate was 82.5 cases, while in the control group, 5 cases were effective, 13 cases were effective, 4 cases were stable, 18 cases were ineffective, and the total effective rate was 45.2%. The curative effect group of TCM syndrome: 0 cases were cured, 5 cases were effective, 28 cases were effective, 7 cases were ineffective, the total effective rate was 82.5%, while in the control group, there were 0 cases of cure, 1 case of remarkable effect, 17 cases of effective, 22 cases of ineffective, and 45 cases of total effective rate. Conclusion: both "general therapy" and "general therapy" can improve the physical and chemical indexes of CKD patients with deficiency of spleen and kidney qi and stagnation of dampness and kidney to some extent, and relieve the clinical symptoms of traditional Chinese medicine. The effect of "general therapy" is better than "general therapy", which shows the advantages of multi-way treatment of chronic kidney disease with deficiency of spleen and kidney qi and dampness and stagnation.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.5

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