针灸治疗顽固性呃逆系统评价

发布时间：2018-05-24 22:39

本文选题：针灸 + 顽固性呃逆　；参考：《成都中医药大学》2016年硕士论文

【摘要】：目的通过Meta分析方法,评价针灸治疗顽固性呃逆的临床疗效与安全性。方法采用计算机检索检索为主、手工检索为辅的方式,以针灸、针刺、艾灸、顽固性呃逆等12个中文词语和16个英文词语为关键词或主题词,区分综合性数据库、会议论文数据库和学位论文数据库3类13个数据库,设置检索时间为2005年至2015年12月30日,全面检索针灸治疗顽固性呃逆相关研究。按照文献纳入与排除标准,确定纳入符合标准文献,提取文献特征,并采用Jadad评分法进行质量评价。最后采用定量分析与定性分析结合的方式,对所纳入研究的临床对照试验进行Meta分析,评价针灸治疗顽固性呃逆的临床疗效与安全性。结果本文共纳入52篇随机对照试验,根据治疗组干预措施的不同区分5个组进行Meta分析。其中针灸联合常规治疗对照常规治疗组纳入8篇文献(681例患者),针灸对照西药组纳入19篇文献(1221例患者),针灸对照针灸组纳入11篇文献(1022)例患者,针灸联合中药对照单纯中药或西药治疗组纳入7篇文献(493例患者),针灸联合西药对照针灸或西药组纳入7篇文献(480例患者)。所有文献均采用“随机”分组,20篇文献描述了具体分组方法；2篇文献使用盲法,但具体实施措施未予以描述；1篇文献进行了样本量估算,但未描述具体估算方法；46篇文献描述基线情况；4篇文献提及脱落与退出,未详细描述具体情况；5篇文献描述不良反应,仅1篇描述具体信息；13篇文献提及随访情况,仅1篇文献描述具体信息；所有文献均未进行ITT分析。整体文献质量较低。Meta分析结果显示：针灸联合常规治疗、针刺联合灸法、针灸联合中药、穴位注射联合耳穴、耳针等治疗顽固性呃逆具有一定效果,优于西药治疗顽固性呃逆。尚不能证明电针、针灸配合西药治疗顽固性呃逆疗效。结论目前国内研究针灸治疗顽固性呃逆的文献数量比较庞大,质量多处于中等偏低水平。针灸联合常规治疗、针刺联合灸法、针灸联合中药、穴位注射联合耳穴、耳针等治疗顽固性呃逆具有一定效果,能够有效缓解或消除呃逆症状。尚不能证明电针、针灸配合西药治疗顽固性呃逆疗效。由于缺乏不良反应数据,无法对针灸治疗顽固性呃逆安全性作出客观评价。
[Abstract]:Objective to evaluate the clinical efficacy and safety of acupuncture and moxibustion in the treatment of intractable hiccup by Meta analysis. Methods 12 Chinese words and 16 English words, such as acupuncture, moxibustion and obstinate hiccup were used as key words or subject words. There were 13 databases of conference papers database and degree thesis database with retrieval time from 2005 to December 30, 2015. The related research on acupuncture and moxibustion treatment of intractable hiccup was comprehensively searched. According to the criteria of literature inclusion and exclusion, the inclusion of standard documents was determined, the characteristics of documents were extracted, and the quality evaluation was carried out by Jadad scoring method. Finally, the clinical efficacy and safety of acupuncture and moxibustion for intractable hiccup were evaluated by Meta analysis. Results A total of 52 randomized controlled trials were included and Meta analysis was performed in 5 groups according to different intervention measures in the treatment group. Among them, the acupuncture and moxibustion combined with conventional therapy and conventional therapy group included 8 literatures (681 patients), the acupuncture and moxibustion control western medicine group included 19 literatures (1221 patients), the acupuncture control group included 11 literatures (1022), and the acupuncture and moxibustion control group (Acupuncture and moxibustion control group) included 11 articles (1022). 493 patients were treated with acupuncture and moxibustion combined with traditional Chinese medicine alone or western medicine, and 480 patients were treated with acupuncture combined with western medicine or western medicine. All the literatures used "random" grouping of 20 articles to describe the specific grouping method and 2 articles using blind method, but the practical measures were not described and 1 document was used to estimate the sample size. However, no specific estimation methods were described in 46 articles describing the baseline situation, 4 references to abscission and withdrawal, 5 cases to adverse reactions described in detail, only 1 article describing specific information and 13 references to follow-up, and 4 references to abscission and withdrawal, only 1 description of specific information and 13 references to follow-up. Only one document described the specific information; none of the literature was analyzed by ITT. The results showed that acupuncture combined with routine therapy, acupuncture combined with moxibustion, acupuncture combined with traditional Chinese medicine, acupoint injection combined with ear points, ear acupuncture and so on, had certain effect in the treatment of intractable hiccup, which was superior to western medicine in the treatment of obstinate hiccup. It is not possible to prove the curative effect of electroacupuncture, acupuncture and western medicine on intractable hiccup. Conclusion the literature on acupuncture and moxibustion in treating obstinate hiccup is large in quantity and low in quality. Acupuncture combined with routine treatment, acupuncture combined with moxibustion, acupuncture combined with traditional Chinese medicine, acupoint injection combined with ear points, ear acupuncture treatment of intractable hiccup has a certain effect, can effectively alleviate or eliminate hiccup symptoms. It is not possible to prove the curative effect of electroacupuncture, acupuncture and western medicine on intractable hiccup. The safety of acupuncture and moxibustion for intractable hiccup can not be evaluated objectively due to the lack of adverse reaction data.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.1

【参考文献】