干眼患者中医证型与焦虑、抑郁的相关性研究

发布时间：2018-05-26 10:59

本文选题：干眼 + 辨证分型　；参考：《南京中医药大学》2017年硕士论文

【摘要】：目的:以中医基础理论为指导,观察和分析干眼(dry eye)患者的中医临床辨证特点,总结出干眼患者中医辨证分型与焦虑、抑郁的相关规律,为临床进一步诊疗提供依据。方法:随机抽取2016年02月-2017年01月就诊于南京市中医院眼科门诊的患者,对符合纳入标准的干眼患者进行问卷调查。运用EpiData软件将调查数据录入后进行整理,采用SPSS20.0软件统计处理。对患者的一般情况,中医辨证分型、年龄、性别、病程以及焦虑、抑郁情绪之间的相关性进行统计分析,研究并总结其中的规律性。结果:干眼患者共126例,其中男性29例,女性共97例,气阴两虚证患者49例,脾胃湿热证患者23例,阴虚湿热证患者54例。干眼患者中医证型与性别、年龄、受教育程度、睡眠时间无关(P0.05),与职业类型、病程长短、MGD、每日接触视频时间相关(P0.05)。干眼患者焦虑、抑郁情绪与性别无关(P0.05),与受教育程度相关(P0.05)。阴虚湿热证患者更易发生焦虑、抑郁,各中医证型间的差异具有统计学意义(P0.05)。结论:干眼患者中脑力劳动者所占比例较大,此类患者以气阴两虚证为主;脾胃湿热证患者更易发生MGD;阴虚湿热证患者病程较长,气阴两虚证患者病程较短。SAS、SDS量表表明:焦虑情绪与受教育程度无关,抑郁情绪与受教育程度呈负相关;HAMA、HAMD量表表明:干眼患者焦虑、抑郁情绪与受教育程度呈负相关。干眼患者以阴虚湿热证发生焦虑、抑郁概率最高,可能与"内火""痰湿"密切相关。在临床诊治干眼患者时可以予以适当的心理干预以及辨证使用疏肝理气药物等治疗。
[Abstract]:Objective: to observe and analyze the clinical syndrome differentiation characteristics of dry eye patients under the guidance of the basic theory of traditional Chinese medicine (TCM), and to summarize the related rules of TCM syndrome differentiation, anxiety and depression in patients with dry eye, so as to provide the basis for further clinical diagnosis and treatment. Methods: randomly selected patients who were admitted to Nanjing traditional Chinese Medicine Hospital from February 2016 to January 2017 were investigated by questionnaire. EpiData software is used to sort out the survey data, and SPSS20.0 software is used to process the data. The general situation of patients, TCM syndrome differentiation, age, sex, course of disease, anxiety and depression were statistically analyzed, and the regularity was studied and summarized. Results: there were 126 patients with dry eye, including 29 males, 97 females, 49 patients with deficiency of qi and yin, 23 patients with damp-heat syndrome of spleen and stomach, 54 patients with damp-heat syndrome of yin deficiency. The TCM syndromes of dry eye patients were not related to sex, age, education, sleep time, and occupational type, duration of disease and MGD. the daily video exposure time was correlated with P0.05. Anxiety and depression in dry eye patients were not related to sex (P 0.05), but to education level (P 0.05). Yin-deficiency damp-heat syndrome patients are more prone to anxiety, depression, the differences among TCM syndrome types have statistical significance (P 0.05). Conclusion: the proportion of mental labors in patients with dry eyes is large, such patients are mainly qi and yin deficiency syndrome, spleen and stomach damp-heat syndrome patients are more prone to MGD, Yin deficiency dampness and heat syndrome patients have a longer course of disease, and the patients with spleen and stomach damp-heat syndrome are more likely to develop MGD. The SDS scale showed that anxiety was not related to education, and depression was negatively related to education. The Hamd scale showed that anxiety, depression and education were negatively correlated in dry eye patients. The patients with dry eyes had the highest probability of anxiety and depression due to yin deficiency, dampness and heat syndrome, which might be closely related to "internal fire" and "phlegm dampness". In clinical diagnosis and treatment of dry eye patients can be given appropriate psychological intervention and dialectical use of drugs such as soothing the liver and regulating qi.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R276.7

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