火针治疗多形性日光疹（肝郁血瘀证）的临床疗效观察

发布时间：2018-05-30 15:44

本文选题：多形性日光疹 + 火针　；参考：《成都中医药大学》2016年硕士论文

【摘要】：目的：通过观察火针治疗多形性日光疹(肝郁血瘀证)的疗效、复发情况及对患者生活质量的影响,评价火针是否为治疗本病证的一种方便、速效、安全、实用的中医治法。方法：纳入病例67例,随机分成两组,治疗组35例,采用火针点刺肝俞、血海及局部皮损,对照组32例,予外用氟芬那酸丁酯软膏。两组疗程均为三周。通过比较两组患者治疗前、治疗第9天、治疗后及随访时的皮损情况(皮损面积、丘疹、结节、苔藓化、表皮剥脱)及自觉症状(瘙痒)的评分变化,于治疗结束进行近期疗效评判,治疗后2月进行远期疗效及复发的评判。应用DLQI量表评价治疗前后患者生活质量的变化情况。所有资料用SPSS21.0进行分析。结果：1、组内比较：治疗前后,两组皮损总积分、各项积分及DLQI积分下降均有统计学差异(P0.01)；2、组间比较：(1)治疗第9天,治疗组皮损总积分较对照组有显著性差异(P0.01)：结节、苔藓化及瘙痒评分均优于对照组(P0.05),其中瘙痒有显著性差异(P0.01)；DLQI积分比较无统计学差异(P0.05)。(2)治疗后,两组近期疗效、皮损总积分均无统计学差异(P0.05)：结节、苔藓化及瘙痒评分均优于对照组(P0.05),其中结节、瘙痒均有显著性差异(P0.01);DLQI评分有统计学差异(P0.05)。(3)随访2月,治疗组在远期疗效、痊愈率及皮损总积分上均优于对照组(P0.05)；DLQI积分有显著差异(P0.01)；治疗组复发率低于对照组(P0.05)。(4)两组安全性及依从性均良好(P0.05)。结论：1、火针与氟芬那酸丁酯软膏治疗多形性日光疹(肝郁血瘀证)均有较好疗效。2、火针治疗起效快,对于结节、苔藓化及瘙痒疗效较好。3、火针治疗多形性日光疹(肝郁血瘀证)远期疗效、降低复发率及对患者生活质量的提高等方面均优于氟芬那酸丁酯软膏。4、火针疗法操作简便,快速有效,不良反应少,安全性高,适合推广使用。
[Abstract]:Objective: to evaluate whether fire acupuncture is a convenient, effective, safe and practical Chinese medicine method for the treatment of this syndrome by observing the curative effect, recurrence and the influence on the quality of life of patients with multiple sunspot rash (liver depression and blood stasis syndrome) by fire acupuncture. Methods: 67 cases were randomly divided into two groups: the treatment group (35 cases) was treated with fire needle needling Ganshu, Xuehai and local skin lesions, and the control group (32 cases) was treated with flufenac butyrate ointment. The course of treatment in both groups was three weeks. The scores of lesions (lesion area, papules, nodules, mossy, epidermis exfoliation) and conscious symptoms (pruritus) were compared between the two groups before, on the 9th day, after treatment and at follow-up. The short-term curative effect was evaluated at the end of treatment, and the long-term effect and recurrence were evaluated 2 months after treatment. The changes of quality of life (QOL) of patients before and after treatment were evaluated with DLQI scale. All data were analyzed by SPSS21.0. Results: before and after treatment, there were significant differences in the total score of skin lesion, the decrease of each score and DLQI score between the two groups (P < 0.01) and the comparison between the two groups on the 9th day of treatment (P < 0.01). The total score of skin lesion in the treatment group was significantly different from that in the control group (P < 0.01), and there was no significant difference between the treatment group and the control group (P < 0.01). The scores of moss and pruritus were better than those of the control group (P 0.05). There was no significant difference in DLQI score between the two groups after treatment. After treatment, there was no significant difference in the short-term curative effect and the total score of skin lesion between the two groups (P 0.05). The scores of moss and pruritus were better than those of the control group (P 0.05). There were significant differences in the scores of nodule and pruritus. There was a significant difference in DLQI score between the two groups. The recovery rate and the total score of skin lesion were significantly higher than that of the control group (P 0.05) and the recurrence rate of the treatment group was lower than that of the control group (P 0.05) and the compliance of the two groups was better than that of the control group (P 0.05). Conclusion both fire needle and flufenac butyrate ointment have good curative effect in treating pleomorphic sunlight rash (liver depression and blood stasis syndrome). The curative effect of mossy and pruritus was better. 3. The long term curative effect of fire acupuncture in the treatment of multiform sunlight rash (liver depression and blood stasis syndrome), reducing the recurrence rate and improving the quality of life of the patients were better than that of flufenac butyl ester ointment. 4. The fire acupuncture therapy was simple and convenient. It is fast and effective, less adverse reaction, high safety and suitable for popularization.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.7

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