活心方加载对冠心病心绞痛患者动脉粥样硬化的影响

发布时间：2018-05-31 04:32

本文选题：活心方 + 冠心病心绞痛　；参考：《时珍国医国药》2017年01期

【摘要】：目的以心踝血管指数(cardio-ankle vascular index,CAVI)、踝臂指数(ankle-brachial index,ABI)、颈动脉内中膜厚度(intima-media thickness,IMT)及脉压(pulse pressure,PP)为观测指标,研究活心方对冠心病心绞痛患者动脉粥样硬化的影响。方法入选58例符合中医气虚血瘀证的冠心病心绞痛患者随机分为中药加载组(30例)和常规治疗组(28例),所有入选患者均采用西药常规治疗,中药加载组患者在西药常规治疗的基础上加用活心方,疗程3个月。分别于治疗前、治疗后检测两组患者的CAVI、ABI、IMT及PP,并进行统计分析。结果经治疗后,中药加载组CAVI、IMT降低,与治疗前及与常规治疗组相比有统计学意义(P0.05);中药加载组PP降低,与治疗前相比有统计学意义(P0.05),但与常规治疗组相比无统计学意义(P0.05);中药加载组ABI升高,但与治疗前及与常规治疗组相比无统计学意义(P0.05)。结论活心方能有效改善动脉粥样硬化,但不能明确对ABI的影响。
[Abstract]:Objective to study the effect of cardio-ankle vascular index (CAVI), ankle brachial index (ankle-brachial index, ABI), carotid artery internal membrane thickness (intima-media thickness, IMT) and pulse pressure (pulse pressure) on atherosclerosis in coronary heart disease patients with angina pectoris. Methods 58 cases were selected to conform to traditional Chinese medicine gas. The patients with coronary heart disease of coronary heart disease with deficiency of blood stasis syndrome were randomly divided into traditional Chinese medicine loading group (30 cases) and routine treatment group (28 cases). All the patients were treated with western medicine routine treatment. The patients in the traditional Chinese medicine loading group were treated with living heart on the basis of conventional treatment of Western medicine for 3 months. Before treatment, the patients were treated with CAVI, ABI, IMT and PP after treatment. Results after treatment, the results showed that after treatment, the CAVI and IMT decreased, compared with the conventional treatment group (P0.05). The PP in the traditional Chinese medicine loading group was significantly lower than that before the treatment (P0.05), but compared with the conventional treatment group (P0.05), but there was no statistical significance compared with the conventional treatment group (P0.05); the ABI in the Chinese medicine loading group was elevated, but before and before the treatment. Compared with the conventional treatment group, there was no statistical significance (P0.05). Conclusion the Huo Xin Fang can effectively improve atherosclerosis, but it can not be clear about the effect of ABI.
【作者单位】：上海中医药大学附属曙光医院;上海市宝山区中西医结合医院;
【基金】：上海市卫生局科研基金资助项目(No.20134153) 上海市进一步加快中医药事业发展三年行动计划资助项目(No.ZY3-JSFC-2-1033;No.ZY3-CCCX-1-1001)
【分类号】：R259

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