中医病证关系的基础研究现状及引入中医体质维度的必要性

发布时间：2018-06-01 01:23

本文选题：疾病 + 中医证候　；参考：《中华中医药杂志》2017年06期

【摘要】：目前,病证关系基础研究主要采用疾病模式,借助分子生物学技术、动物模型等,揭示疾病背景下证候差异的生物学基础、证候的动态演变规律以及证候对疾病发展、转归的影响,取得了一定的研究成果。然而,证候差异研究因受疾病因素的影响,不足以揭示机体个体差异的本质,脱离体质研究个体差异有失偏颇;证候模型难以兼顾动态性和个体差异性两个方面,兼顾体质、疾病、证候3个因素的模型亟待开发;证候对疾病的影响尚缺少疾病"发生"阶段的研究,引入"体质"维度可完善发生阶段的研究。提出,突破目前的疾病模式,开展"体质""证候""疾病"3个维度的研究,探索体质个体差异对疾病和证候的影响,完善病证关系研究,体现中医个体化和治未病优势。
[Abstract]:At present, the basic research on the relationship between disease and syndrome mainly adopts the disease model, with the help of molecular biology technology and animal model, to reveal the biological basis of the syndrome difference under the disease background, the dynamic evolution law of the syndrome, and the development of the syndrome to the disease. The influence of the result, obtained certain research result. However, because of the influence of disease factors, the study of syndrome difference is not enough to reveal the nature of individual difference of body, it is biased to break away from the individual difference of physique study, the syndrome model is difficult to take into account both dynamic and individual differences, The models of three factors of disease and syndromes need to be developed urgently, and the influence of syndrome on disease is still short of the study on the stage of disease "occurrence", which can be improved by introducing the dimension of "constitution". It is suggested that the research on three dimensions of "constitution" and "syndrome" and "disease" should be carried out through breaking through the current disease pattern, exploring the influence of individual difference of constitution on disease and syndrome, perfecting the research on the relationship between disease and syndrome, and embodying the superiority of individualization and treatment of disease in TCM.
【作者单位】：北京中医药大学;
【基金】：国家自然科学基金青年科学基金项目(No.81503471) 北京中医药大学自主课题(No.2015-JYB-JSMS004)~~
【分类号】：R22

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