五神针治疗肝肾不足型血管性痴呆的临床研究

发布时间：2018-06-01 18:49

本文选题：五神针 + 肝肾不足型　；参考：《时珍国医国药》2017年07期

【摘要】：目的观察五神针治疗肝肾不足型血管性痴呆的临床疗效。方法将180例肝肾不足型血管性痴呆患者随机分为基础治疗组、传统针刺组和五神针组,每组各60例。基础治疗组进行常规的基础治疗,传统针刺组在基础治疗组治疗基础上取传统针刺穴位进行治疗,五神针组在基础治疗组治疗基础上针刺百会,四神聪为主穴进行治疗,疗程均为28d。比较各组治疗前后长谷川痴呆量表(HDS)、日常生活能力量表(ADL)和简易精神状态量表(MMSE)的评分;检测治疗前后超氧化物歧化酶(SOD)、血浆降钙素基因相关肽(CGRP)和丙二醛(MDA)的变化。结果基础治疗组脱落1例,传统针刺组脱落3例,五神针组脱落2例,治疗后五神针组总有效率94.8%,显著高于基础治疗组69.5%和传统针刺组的82.5%(均P0.01);五神针组HDS、ADL和MMSE评分较基础治疗组和传统针刺组改善更为显著(均P0.05);五神针组SOD、CGRP和MDA水平的改善优于基础治疗组和传统针刺组(均P0.05)。结论五神针组可显著提高肝肾不足型血管性痴呆患者的HDS、ADL和MMSE评分,改善SOD、CGRP和MDA的水平,其临床疗效优于基础治疗组和传统针刺组。
[Abstract]:Objective to observe the clinical effect of Wushen acupuncture on vascular dementia with deficiency of liver and kidney. Methods 180 cases of vascular dementia with deficiency of liver and kidney were randomly divided into basic treatment group, traditional acupuncture group and Wushen acupuncture group with 60 cases in each group. The basic treatment group was treated with routine basic treatment, the traditional acupuncture group took the traditional acupuncture points for treatment on the basis of the basic treatment group, the Wushen acupuncture group treated Baihui on the basis of the basic treatment group, and the main points of Sishencong were treated. The course of treatment was 28 days. The scores of HDS, ADL and MMSE were compared before and after treatment, and the changes of superoxide dismutase (SOD), plasma calcitonin gene-related peptide (CGRP) and malondialdehyde (MDA) were measured before and after treatment. Results one case in the basic treatment group, 3 cases in the traditional acupuncture group and 2 cases in the Wushen acupuncture group. After treatment, the total effective rate of Wushen acupuncture group was 94.8%, which was significantly higher than that of the basic treatment group (69.5%) and the traditional acupuncture group (82.5%) (P < 0.01), and the scores of MMSE and MMSE in the Wushen acupuncture group were significantly better than those in the basic treatment group and the traditional acupuncture group (all P 0.05); the scores of SODCGRP and MDA water in the Wushen acupuncture group were significantly better than those in the basic treatment group and the traditional acupuncture group (P < 0.05). The improvement of pingping was better than that of basic treatment group and traditional acupuncture group (P 0.05). Conclusion Wushen acupuncture group can significantly improve the scores of MMSE and ADL in patients with vascular dementia with liver and kidney deficiency, and improve the levels of MDA and CGRP in patients with liver and kidney deficiency vascular dementia. The clinical efficacy of Wushen acupuncture group is better than that of basic treatment group and traditional acupuncture group.
【作者单位】：河南中医药大学针灸推拿学院;河南中医药大学第三附属医院;
【基金】：河南省中医药大学博士科研基金项目(No.BSJJ2014-21)
【分类号】：R246.6

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