火针疗法在体外受精-胚胎移植中的应用时点与效应观察

发布时间：2018-06-05 19:20

本文选题：体外受精-胚胎移植(IVF-ET) + 火针疗法　；参考：《中国针灸》2017年05期

【摘要】：目的:观察在月经周期特定时点进行火针干预对子宫微环境的影响,以评价其在辅助生殖中的效应。方法:将68例接受体外受精-胚胎移植(IVF-ET)的患者随机分为观察组(35例)和对照组(33例)。两组患者均采用江苏省人民医院临床生殖中心微刺激方案进行IVF-ET和移植后黄体支持。对照组采用针灸序贯疗法常规方案治疗;观察组在对照组的基础上,在排卵后(排卵后第1d,时点1)及经前期末期(月经前3d,时点2)分别进行火针干预,时点1穴取肾俞、命门、腰阳关;时点2穴取肾俞、次毼,针刺顺序先上后下,先左后右。观察两组患者备孕期中医证候的改变,并比较两组患者移植日子宫内膜厚度、形态及移植后生化妊娠率和临床妊娠率。结果:治疗后两组中医证候积分均降低(均P0.05);观察组的生化妊娠率、临床妊娠率均稍高于对照组,但是组间差异无统计学意义(均P0.05);观察组移植日的子宫内膜厚度大于对照组(P0.05);两组治疗后中医证候积分、子宫内膜类型比较差异均无统计学意义(均P0.05)。结论:月经周期特定时点火针干预可以改善不孕患者月经症状,增加子宫内膜厚度,进而辅助胚胎着床。
[Abstract]:Aim: to observe the effect of fire needle intervention on uterine microenvironment at a specific point in menstrual cycle to evaluate its effect in assisted reproduction. Methods: Sixty-eight patients undergoing IVF-ET were randomly divided into observation group (n = 35) and control group (n = 33). Both groups were treated with IVF-ET and luteal support after transplantation. The control group was treated with routine acupuncture and moxibustion sequential therapy, and the observation group was treated with fire needle intervention after ovulation (1 day after ovulation) and at the end of premenstrual period (3 days before menstruation, 2 at time) on the basis of control group. Yaoyang pass; point 2 points to take Shenshu, secondary, acupuncture sequence first up and then down, first left and then right. The changes of TCM syndromes during pregnancy were observed and the endometrial thickness, morphology, biochemical pregnancy rate and clinical pregnancy rate were compared between the two groups. Results: after treatment, the scores of TCM syndromes in the two groups were all decreased (P 0.05), the biochemical pregnancy rate and the clinical pregnancy rate in the observation group were slightly higher than those in the control group. However, there was no significant difference between the two groups (all P 0.05); the thickness of endometrium in the observation group was larger than that in the control group (P 0.05); there was no significant difference in TCM syndromes score and endometrial type between the two groups after treatment (all P 0.05). Conclusion: fire acupuncture intervention can improve menstrual symptoms, increase endometrial thickness and assist embryo implantation in infertile women.
【作者单位】：南京医科大学第一附属医院江苏省人民医院针灸科;
【基金】：江苏省中医药管理局资助项目:YB 2015167
【分类号】：R246.3

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