疏肝和胃抑酸降逆法治疗非糜烂性胃食管反流病肝胃不和证的临床观察
发布时间:2018-06-08 07:20
本文选题:胃食管反流病 + 非糜烂性胃食管反流病 ; 参考:《黑龙江中医药大学》2017年硕士论文
【摘要】:目的:通过疏肝和胃抑酸降逆法治疗非糜烂性胃食管反流病肝胃不和证的临床观察,评定其疗效。方法:本研究在临床上以治疗前后自身对照的方法作为研究方法,对中医辨证符合纳入标准的46名非糜烂性胃食管反流病肝胃不和证患者进行治疗,按患者就诊的先后顺序进行编号,予以基础治疗以及中药疏肝和胃抑酸降逆法治疗,治疗时间为4周。观察并记录患者治疗前后的中医症状变化情况及胃食管反流病问卷积分情况。并于停药后4周时,进行电话随机访问,填写GerdQ问卷,利用症状积分统计复发情况。将所得数据结果录入SPSS22.0软件进行数据分析。结果:临床治疗过程中脱落患者2例,完成治疗的患者共44例,疗程结束后中医证候疗效统计结果为痊愈2例,占4.54%,显效5例,占11.36%,有效35例,占79.54%,无效2例,占4.54%,中医证候总有效率为95.45%。治疗前与疗程结束后中医证候总积分(24.32±2.75,9.73±3.28),经统计学分析,Z=-5.78,P0.01,具有统计学意义。在单项证候积分方面,治疗前后单项症泛酸(5.32±1.05,1.86±1.00)、烧心(4.77±1.16,2.41±1.34)、胸骨后疼痛,牵及两肋(4.05±1.46,1.77±1.08)、嗳气(4.36±1.16,1.82±0.95)、纳差(1.48±0.88,0.45±0.50)、情绪不畅加重(1.57±0.73,0.52±0.59)、打呃(1.59±0.66,0.55±0.50)、恶心(1.18±0.58,0.34±0.48)病情程度比较,差异有统计学意义。治疗前与治疗后GerdQ问卷积分分别为14.55±1.90与7.32±1.30,经统计学分析Z=-5.79,P0.01。统计复发情况为44例中复发4例,复发率为9.09%。结论:1、疏肝和胃抑酸降逆法可有效改善非糜烂性胃食管反流病肝胃不和证患者的中医症状。2、疏肝和胃抑酸降逆法可明显降低非糜烂性胃食管反流病肝胃不和证患者的复发率。
[Abstract]:Objective: to evaluate the curative effect of the treatment of non-erosive gastroesophageal reflux disease with disharmony of liver and stomach. Methods: in this study, 46 patients with non-erosive gastroesophageal reflux syndrome were treated with self-control before and after treatment. The patients were treated with basic treatment and traditional Chinese medicine for 4 weeks. To observe and record the changes of TCM symptoms and the score of gastroesophageal reflux disease questionnaire before and after treatment. At 4 weeks after withdrawal, random telephone interview was conducted, GerdQ questionnaire was filled out, and recurrence was counted by symptom score. Input the data results into SPSS 2 2.0 software for data analysis. Results: in the course of clinical treatment, there were 2 cases of shedding patients and 44 cases of complete treatment. After the course of treatment, 2 cases were cured (4.54%), 5 cases were markedly effective, 11.36% were effective, 35 cases were effective, 79.54 cases were not effective, and 2 cases were ineffective. The total effective rate of TCM syndrome was 95.4545. The total score of TCM syndromes before treatment and after treatment was 24.32 卤2.75 卤9.73 卤3.28, which was statistically significant by statistical analysis. 鍦ㄥ崟椤硅瘉鍊欑Н鍒嗘柟闈,
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