金石止痛汤治疗慢性结石性胆囊炎肝胆湿热型的临床观察

发布时间：2018-06-08 11:52

本文选题：慢性结石性胆囊炎 + 肝胆湿热型　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:通过金石止痛汤对慢性结石性胆囊炎肝胆湿热型患者的治疗,观察结石大小改变情况及临床症状体征变化情况,以评定其疗效。方法:将符合纳入标准的患者42名按就诊的先后顺序进行编号,采用治疗前后自身对照研究,予金石止痛汤治疗,2次/日,早晚饭前30min 口服,疗程6周。治疗结束后,观察治疗前后的各项指标,进行整理及统计分析。结果:1.经金石止痛汤治疗后,结石大小改变的有效率为57.89%。治疗前后结石直径数值进行比较分析,不符合正态分布,经统计学两组相关样本非参数检验分析,Z=-4.124,P0.01,治疗前后结石直径数值有显著差异,具有统计学意义。2.中医症候临床疗效的有效率为94.74%。经配对样本t检验分析,t=20.399,P0.01,治疗前后中医证候积分有显著差异,具有统计学意义。3.经治疗后彩超影像学的有效率为86.84%。经统计学两组相关样本非参数检验分析,Z=-5.298,P0.01,认为治疗前后彩超积分有显著差异,具有统计学意义。结论:1.金石止痛汤对改善慢性结石性胆囊炎肝胆湿热型患者的中医症状及体征有显著疗效。2.金石止痛汤能改善慢性结石性胆囊炎肝胆湿热型患者的彩超影像学表现。3.金石止痛汤对胆囊结石有一定的治疗作用。
[Abstract]:Objective: to evaluate the curative effect of Jinshi Zhitong decoction on chronic cholecystitis with dampness and heat of liver and gallbladder, and to observe the change of stone size and clinical symptoms and signs. Methods: 42 patients who met the inclusion criteria were numbered according to the order of their visits. The patients were treated with Jinshi Zhitong decoction twice a day before and after treatment. The patients were treated with 30min for 6 weeks in the morning and evening. After the treatment, the indexes before and after treatment were observed and analyzed statistically. The result is 1: 1. After treatment with Jinshi Zhitong decoction, the effective rate of stone size change was 57.89. The stone diameter value before and after treatment was not in accordance with the normal distribution. The stone diameter value was significantly different before and after treatment by non-parametric test analysis of the two groups of related samples. The effective rate of clinical curative effect of TCM symptom is 94.74. By paired t-test analysis, the score of TCM syndromes was significantly different before and after treatment, with statistical significance .3.The results showed that there were significant differences in the scores of TCM syndromes before and after treatment. After treatment, the effective rate of color ultrasound imaging was 86.84. The non-parametric analysis of the two groups of related samples showed that there was a significant difference in the color ultrasound score before and after treatment and had statistical significance. Conclusion 1. Jinshi Zhitong decoction has a significant effect on improving the symptoms and signs of chronic gallstone cholecystitis in patients with dampness and heat of liver and gallbladder. Jinshi Zhitong decoction can improve the imaging features of chronic gallstone cholecystitis with dampness and heat of liver and gallbladder. Jinshi Zhitong decoction has certain therapeutic effect on gallstone.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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