电针治疗神经病理性疼痛的系统评价

发布时间：2018-06-08 20:59

本文选题：电针 + 神经病理性疼痛　；参考：《中国现代医生》2017年02期

【摘要】：目的系统评价电针对神经病理性疼痛的有效性和安全性。方法计算机检索CNKI、Wan Fang Data、VIP、CBM、EMbase、Pub Med和The Cochrane Library,查找电针治疗神经病理性疼痛的随机对照研究,治疗组采用电针或电针联合其他常规治疗,对照组采用常规治疗,检索时限从1996年10月~2016年10月。由两位研究者独自按照纳入和排除标准筛选文献并提取资料,然后采用Cochrane风险偏倚评估工具对纳入文献进行偏倚风险评估。采用Rev Man 5.3软件进行Meta分析。结果最终纳入17篇文献,共1107例受试者。Meta分析结果显示:在提高治疗总有效率方面,治疗组优于对照组[OR=3.77,95%CI(2.61,5.46),P0.00001],而在降低VAS评分[MD=-0.29,95%CI(-0.65,0.06),P=0.10]、降低复发率[OR=0.47,95%CI(0.12,1.94),P=0.30]方面,治疗组与对照组无差异。结论电针干预神经病理性疼痛可以提高总有效率,而降低VAS评分、降低疾病复发率方面与对照组无差异。但受纳入研究样本量所限,该结论尚需更多高质量实验验证。
[Abstract]:Objective to evaluate the efficacy and safety of electroacupuncture in the treatment of neuropathic pain. Methods to search the CNKI Wan Fang Fang data VIPP CBM base pub Med and the Cochrane Library, to find out the randomized controlled study of electroacupuncture in the treatment of neuropathic pain. The treatment group was treated with electroacupuncture or electroacupuncture combined with other routine therapy, while the control group was treated with routine therapy. The time limit of retrieval was from October 1996 to October 2016. According to the inclusion and exclusion criteria, the two researchers independently sifted the literature and extracted the data, and then used the Cochrane risk bias assessment tool to evaluate the bias risk of the inclusion literature. Meta-analysis was carried out by using Revman 5.3 software. Results A total of 1107 subjects. Meta-analysis results showed that the treatment group was superior to the control group in improving the total effective rate of treatment [OR3.77-95CI2.61C 2.61C 5.46C P 0.00001], but there was no difference between the treatment group and the control group in reducing the VAS score [MD-0.29C95 CI-0.650.06P0.10] and the relapse rate [OR0.4795 / 95 CI 0.121.94 P0. 30]. Conclusion Electro-acupuncture intervention in neuropathic pain can improve the total effective rate, but decrease the VAS score and reduce the recurrence rate of neuropathic pain. However, limited by the sample size, this conclusion needs more high-quality experimental verification.
【作者单位】：浙江中医药大学附属第三医院针灸科;
【基金】：浙江省重点科技创新团队(2013TD15) 浙江省中医药科研基金项目(2015ZA116、2016ZA109)
【分类号】：R246.6

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