周世印教授脂肪肝学术思想与清热利湿法治疗非酒精性脂肪肝临床研究

发布时间：2018-06-10 05:05

本文选题：周世印教授 + 临床经验　；参考：《河南中医药大学》2016年硕士论文

【摘要】：目的继承名老中医宝贵的学术思想和临床经验是中医传承和发展的有效途径,导师周世印教授从医50余载,中医理论功底深厚,临床经验丰富,全面研究和继承周世印教授治疗内科疾病的学术思想和临床经验,并指导临床实践,具有十分重要的意义。方法通过文献和理论研究,系统整理和挖掘周世印教授的学术思想渊源,进行深入的分析,形成指导临床的理论。通过跟师学习,总结导师的辨证论治经验,并在门诊筛选非酒精性脂肪肝患者80例,每组40例,分别服用中药清热利湿方与西药多烯磷脂酰胆碱胶囊对照研究,比较临床疗效。结果第一部分:周世印教授学术渊源。论述了周世印教授学术思想形成过程及临床经验总结。周世印教授经过系统地中医理论学习,基础扎实。其学术思想体系源于《内经》《伤寒论》,受《脾胃论》影响深刻,同时深受岳美中、郑颉云等中医名家的学术熏陶。第二部分:周世印教授脂肪肝学术思想和临床经验总结。周师学术思想:认为湿邪是脂肪肝的主要发病因素,重视舌诊对脂肪肝的诊断意义,强调临床要分型辨证施治,尤其强调脂肪肝的治疗要重视调养脾胃,治病求本。周师临床经验:认为本病发病原因与湿、痰、瘀、积相关,其中痰湿血瘀占主导地位,引起肝、脾、肾功能失调,湿热痰瘀互结于肝,临床上对于本病的治法多以以燥湿化痰、活血化瘀为主。第三部分:清热利湿法治疗非酒精性脂肪性肝(肝胆湿热型)的临床研究。研究表明该方安全可靠,能够明显改善患者的临床症状和体征,显著改善肝功、血脂、肝/脾比值,与当今临床治疗非酒精性脂肪肝病常用药多烯磷脂酰胆碱胶囊相比,具有明显优势。结论本研究首次系统挖掘、整理了周世印教授有关脂肪肝的学术渊源和临床经验,升华其学术思想,提出用清热利湿法治疗肝胆湿热型脂肪肝,并进行验证,有鲜明的创新性和实用性。以期推动中医药治疗脂肪肝的学术传承、创新和发展。
[Abstract]:Objective to inherit the valuable academic thought and clinical experience of famous Chinese medicine is an effective way for the inheritance and development of traditional Chinese medicine. Professor Zhou Shiyin, a tutor, has been in medicine for more than 50 years, with profound theoretical foundation and rich clinical experience in traditional Chinese medicine. It is of great significance to study and inherit Professor Zhou Shiyin's academic thought and clinical experience in the treatment of internal diseases and to guide clinical practice. Methods through the research of literature and theory, the author systematically sorted out and excavated the academic thought origin of Professor Zhou Shiyin, carried on the thorough analysis, formed the theory guiding the clinic. By learning from the teacher and summarizing the experience of differentiation and treatment, 80 cases of non-alcoholic fatty liver were selected in the outpatient department, 40 cases in each group. The comparative study of traditional Chinese medicine Qingre Li-li recipe and western medicine polyenylphosphatidylcholine capsule was carried out to compare the clinical efficacy. Results the first part: professor Zhou Shiyin academic origin. The forming process and clinical experience of Professor Zhou Shiyin's academic thought are discussed. Professor Zhou Shiyin has studied Chinese medicine theory systematically and has a solid foundation. His academic thought system originated from the Internal Classic and the Theory of febrile Diseases, and was deeply influenced by spleen and stomach, and also deeply influenced by the academic edification of some famous Chinese medicine scholars such as Yuemei Zhong, Zheng Jieyun and so on. The second part: professor Zhou Shiyin's academic thought and clinical experience of fatty liver. Zhou Shi's academic thought: it is believed that dampness is the main pathogenic factor of fatty liver, paying attention to the diagnostic significance of tongue diagnosis on fatty liver, emphasizing clinical differentiation of symptoms and signs, and especially emphasizing that the treatment of fatty liver should pay attention to nourishing spleen and stomach and treating diseases and seeking the root of disease. Zhou Shi's clinical experience: the cause of this disease is related to dampness, phlegm, blood stasis and accumulation, in which phlegm, dampness and blood stasis play a dominant role, causing the dysfunction of liver, spleen, kidney, dampness and heat phlegm and blood stasis. Promoting blood circulation and removing blood stasis are the main factors. The third part: the clinical study on the treatment of non-alcoholic fatty liver (liver and gallbladder dampness-heat type) with the method of clearing away heat and promoting dampness. The study shows that the prescription is safe and reliable, can obviously improve the clinical symptoms and signs, liver function, blood lipid, liver / spleen ratio, compared with the current clinical treatment of non-alcoholic fatty liver disease commonly used Polyene phosphatidylcholine capsule, It has obvious advantages. Conclusion for the first time, this study systematically excavated Professor Zhou Shiyin's academic origin and clinical experience about fatty liver, sublimated his academic thought, and put forward the treatment of fatty liver of liver and gallbladder damp-heat type with the method of clearing away heat and heat, and verified it. It is innovative and practical. In order to promote the treatment of fatty liver Chinese medicine academic heritage, innovation and development.
【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R249;R259

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