柏硝洗剂湿敷促进肛瘘术后创面愈合的临床观察

发布时间：2018-06-14 18:10

本文选题：柏硝洗剂 + 低位单纯性肛瘘　；参考：《河南中医药大学》2016年硕士论文

【摘要】：目的:通过观察柏硝洗剂对创面湿敷在促进肛瘘术后愈合过程中的创面疼痛、水肿程度、创面渗液程度、显微镜下观察创面新生肉芽组织的成纤维细胞数量和创面愈合时间这几项指标,探讨柏硝洗剂加速创面愈合的机理,从而对柏硝洗剂的临床应用提出科学、可靠的理论依据。方法:将60例符合本研究入选标准的低位单纯性肛瘘术后病人,随机地分成治疗组及对照组各30例,两组患者在常规换药和红光照射的基础上,从术后第一天起治疗组使用柏硝洗剂50ml用隔袋温热后将一块医用纱布浸湿后放至创面进行湿敷,每次湿敷20min,早晚各一次;而对照组采用金玄痔科熏洗散一袋,加1000ml开水化开后,趁热先熏蒸肛门,再坐浴,每次20分钟,早晚各一次。观察两组病人的创面愈合时间及术后3、7、12天两组患者间疼痛、水肿程度、创面渗液程度和术后第7、12天显微镜下观察创面新生肉芽组织的成纤维细胞数量的差别。结果:柏硝洗剂在创面愈合时间方面与对照组相比较平均约提前3天,有显著差异(P0.01)。同时,柏硝洗剂在减轻术后创面疼痛、水肿、渗液及提高创面肉芽组织的成纤维细胞数量方面仍较对照组有显著优势(P0.05)。结论:经观察研究,柏硝洗剂具有清热燥湿、解毒消肿疗疮的临床疗效,通过使用柏硝洗剂对术后的创面进行湿敷可以明显缓解术后患者的创面疼痛、水肿程度及创面渗液的现象,能加速术后创面组织的成纤维细胞增殖,进而可以减少患者创面的愈合时间,可作为加速肛瘘术后创面愈合的有效方法,无明显不良反应。
[Abstract]:Objective: to observe the degree of wound pain, edema and exudation in the process of promoting the healing of anal fistula by wet application of Burnite lotion. The number of fibroblasts and wound healing time of new granulation tissue were observed under microscope, and the mechanism of Burberry lotion to accelerate wound healing was discussed. The scientific and reliable theoretical basis for clinical application of Burnite lotion was put forward. Methods: sixty patients with low simple anal fistula were randomly divided into treatment group (n = 30) and control group (n = 30). From the first day after operation, the treatment group was treated with 50ml, then soaked a piece of medical gauze and put it into the wound for 20 minutes each time, once in the morning and evening, while the control group was treated with Jinxuan Zhike fumigation and washing powder, and then opened with 1000ml boiling water. Fumigation anus while hot, sit bath again, 20 minutes each time, morning and evening each time. The time of wound healing and the degree of pain, edema, exudation of wound surface and the number of fibroblasts of new granulation tissue were observed under microscope on the 712th day after operation. Results: compared with the control group, the healing time of Burnite lotion was 3 days earlier than that of the control group (P 0.01). At the same time, P0. 05 lotion still had a significant advantage over the control group in relieving pain, edema, exudation and increasing the number of fibroblasts in granulation tissue after operation. Conclusion: through observation and study, the Burnite lotion has the clinical curative effect of clearing heat, dryness and dampness, detoxification and detumescence, and can relieve the pain of the wounds after operation by wet application of Burnite lotion. The degree of edema and the phenomenon of wound exudation can accelerate the proliferation of fibroblasts in wound tissue and reduce the wound healing time. It can be used as an effective method to accelerate the wound healing after anal fistula operation without obvious adverse reactions.
【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R266

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