除湿通痹方治疗急性痛风性关节炎的临床疗效观察

发布时间：2018-06-17 06:55

本文选题：急性痛风性关节炎 + 除湿通痹　；参考：《云南中医学院》2017年硕士论文

【摘要】：目的:对比研究除湿通痹方、白虎加桂枝汤合宣痹汤加减方治疗急性痛风性关节炎红肿热痛等症状的临床疗效。方法:将2014年10月-2016年10月共收集70例纳入本研究,运用随机数字表分组法,其中观察组35例,对照组35例。观察过程中因依从性差、病例脱落等原因,最终观察组32例,对照组32例。最终数据统计分析按64病例进行研究,通过观察除湿通痹方、白虎加桂枝汤合宣痹汤加减方对急性痛风性关节炎患者发病关节疼痛、肿胀、发热、功能等症状积分的影响,来评价除湿通痹方治疗急性痛风性关节炎的临床疗效。结果:1.总体有效率评价:观察组治疗后,其中临床痊愈4例,显效8例,有效19例,无效1例,总有效率96.86%;对照组治疗后,临床痊愈2例,显效5例,有效21例,无效4例,总有效率87.50%。观察组疗效优于对照组。2.观察组与对照组经过治疗后,症状总积分均明显改善,P0.001。3.观察组关节肿胀的症状积分改善程度明显优于对照组,P0.001,观察组关节功能障碍的症状积分较对照组下降更多,P0.05。结论:除湿通痹方在减轻急性痛风性关节炎患者关节疼痛、压痛、表面皮色、发热、受累关节数,尤其是关节肿胀、功能障碍方面具有良好的作用。表明除湿通痹方在急性痛风性关节炎的治疗中具有一定的应用价值,体现了中医辨证施治以及中药的优势。
[Abstract]:Objective: to compare the clinical effect of dehumidification Tongbi prescription, Baihu plus Guizhi decoction and Xuanbi decoction in treating acute gouty arthritis. Methods: a total of 70 cases were collected from October 2014 to October 2016 and randomly divided into two groups: observation group (n = 35) and control group (n = 35). There were 32 cases in the observation group and 32 cases in the control group because of poor compliance and abscission. The final data were statistically analyzed according to 64 cases. By observing the effects of Qishitongbi recipe, Baihu plus Guizhi decoction and Xuanbi decoction on the joint pain, swelling, fever and function in patients with acute gouty arthritis, To evaluate the clinical efficacy of dehumidification Tongbi prescription in the treatment of acute gouty arthritis. The result is 1: 1. The overall effective rate was evaluated as follows: in the observation group, 4 cases were clinically cured, 8 cases were markedly effective, 19 cases were effective, 1 case was ineffective, and the total effective rate was 96.86 cases, while in the control group, 2 cases were cured, 5 cases were markedly effective, 21 cases were effective, 4 cases were ineffective. The total effective rate is 87.50. The curative effect of the observation group was better than that of the control group. After treatment, the total symptom scores of the observation group and the control group were significantly improved (P 0.001.3). The symptom score of joint swelling in the observation group was significantly better than that in the control group (P 0.001), and the symptom score of joint dysfunction in the observation group was much lower than that in the control group (P 0.05). Conclusion: Dishitongbi prescription has a good effect on relieving joint pain, tenderness, skin color, fever, number of affected joints, especially joint swelling and dysfunction in patients with acute gouty arthritis. It shows that the prescription of removing dampness and Tongbi has certain application value in the treatment of acute gouty arthritis, which embodies the advantages of TCM syndrome differentiation and traditional Chinese medicine.
【学位授予单位】：云南中医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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