中药代茶饮治疗肺肾阴虚型慢性咽炎的临床研究

发布时间：2018-06-18 06:12

本文选题：中药代茶饮自拟方 + 肺肾阴虚型　；参考：《新疆医科大学》2017年硕士论文

【摘要】：目的:本课题通过观察中药代茶饮自拟方治疗肺肾阴虚型慢性咽炎的临床疗效,对其疗效进行评价,并初步分析其作用机理,从而探索该方治疗肺肾阴虚型慢性咽炎的疗效,为中医药治疗慢性咽炎提供一定的依据。方法:本课题分三个步骤进行:1.依据目前公认的标准制定诊断标准、辨证分型,确立纳入标准、排除标准、剔除和脱落标准、观察指标、积分标准、疗效判定标准等。2.选择慢性咽炎中符合肺肾阴虚型的患者60例,按照随机对照、非盲法的临床试验原则分为两组,试验组30例给予中药代茶饮自拟方加六味地黄丸,对照组30例仅给予六味地黄丸,疗程均为10天。治疗过程中观察并记录两组患者的临床症状、局部体征变化及不良反应。3.将收集的资料进行整理、统计学分析。结果:1.两组患者中,试验组总有效率为78.57%,对照组总有效率为57.89%。经X2检验:X2=8.629,P=0.0350.05,差异有统计学意义,提示中药代茶饮自拟方加六味地黄丸在改善肺肾阴虚型慢性咽炎患者的症状、体征方面优于仅用六味地黄丸。2.对影响两组患者疗效的相关因素做logistic回归分析比较后发现,年龄、性别的OR值分别为0.351、0.734,均小于1,病程的OR值为1.466,大于1,因此认为年龄、性别不是影响疗效的因素,而病程是影响疗效的因素。结论:本研究结果表明,中药代茶饮自拟方治疗肺肾阴虚型慢性咽炎具有较好的疗效,特别在减轻患者症状、改善患者体征方面,显示了中药代茶饮自拟方治疗肺肾阴虚型慢性咽炎的优势,值得临床推广和进一步的研究开发。
[Abstract]:Objective: to observe the clinical curative effect of traditional Chinese medicine on treating chronic pharyngitis with deficiency of lung and kidney yin, evaluate its curative effect, and analyze its mechanism, so as to explore the curative effect of this prescription in treating chronic pharyngitis with deficiency of lung and kidney yin. To provide a certain basis for the treatment of chronic pharyngitis with traditional Chinese medicine. Methods: this subject is divided into three steps: 1. To establish diagnostic criteria, syndrome differentiation, inclusion criteria, exclusion criteria, observation indicators, integral criteria, curative effect criteria and so on according to the current accepted criteria. 2. Sixty patients with chronic pharyngitis according to the type of deficiency of lung and kidney yin were divided into two groups according to the principle of randomized control and non-blind clinical trial. 30 cases in the test group were given Chinese medicine to substitute tea drink and Liuwei Dihuang pill. The control group (30 cases) was treated with Liuwei Dihuang pills for 10 days. The clinical symptoms, local signs and adverse reactions were observed and recorded during the treatment. Collect the data to sort out, statistical analysis. The result is 1: 1. The total effective rate was 78.57 in the trial group and 57.89 in the control group. By X2 test, the difference was statistically significant, indicating that Chinese herbal tea decoction and Liuwei Dihuang pill were better than only Liuwei Dihuang pills in improving symptoms and signs of chronic pharyngitis of lung and kidney yin deficiency type. Logistic regression analysis showed that the OR values of age and sex were 0.351 卤0.734, respectively, and the OR value of course of disease was 1.466, which was greater than 1. Therefore, age and sex were not the factors influencing the curative effect. The course of disease is the factor that affects the curative effect. Conclusion: the results of this study indicate that the Chinese herbal recipe for tea drinking has a better curative effect on chronic pharyngitis with deficiency of lung and kidney yin, especially in alleviating the symptoms and improving the physical signs of the patients. It shows the advantages of traditional Chinese medicine for the treatment of chronic pharyngitis with deficiency of lung and kidney yin, which is worthy of clinical popularization and further research and development.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R276.1

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