中医药治疗血管性认知障碍的文献研究及补肾化痰活血法治验总结
发布时间:2018-06-19 22:56
本文选题:血管性认知障碍 + 中医药治疗 ; 参考:《辽宁中医药大学》2017年硕士论文
【摘要】:目的:将近十年中医药治疗血管性认知障碍文献研究所获得的本病辨证治疗及用药规律与导师应用补肾化痰活血法治疗本病的临床经验相对比,以文献研究结果验证临床用药,并拓宽治疗思路,为临床用药提供指导,以求在今后的临床实践中获得更好的疗效。材料与方法:收集中医药治疗血管性认知障碍的临床研究文献106篇,整理所收集文献的辨证治疗及用药情况,建立相关数据库,以证素辨证理论为依据,并应用Microsoft Excel软件对数据进行处理,分析文献治疗本病的辨证治疗及用药规律;基于临床实践,总结刘君教授运用补肾化痰活血法治疗血管性认知障碍的临床经验。结果:1.本研究纳入的106篇文献中,共涉及45种证型、16项通用证素、21种治法及150味中药。其中,最常见的证型为肾精亏虚兼痰瘀阻滞证,常见的病性证素及其所占比重依次为血瘀(71.70%)、痰(43.40%)、精亏(42.45%),最常见的病位证素为肾;常用治法及其所占比重依次为:活血化瘀(96.23%)、健脾化痰(47.17%)、补肾益精(38.68%)。2.最常使用的单味药为石菖蒲。3.所涉及的150味中药中,药性分布为:温(48.97%)、寒(24.25%)、平(22.20%)、凉(3.64%)、热(0.93%);药味分布为:甘(29.78%)、苦(28.42%)、辛(24.94%)、咸(7.78%)、酸(4.30%)、涩(3.30%)、淡(1.47%);多入肝经(24.60%)、心经(15.92%)、肾经(13.58%)及脾经(13.35%);根据功效分类多为活血化瘀药(20.52%)、补血药(10.45%)及补气药(10.17%)。4.补肾化痰活血法治疗血管性认知障碍疗效确切。结论:血管性认知障碍的发生与肾精亏虚、痰浊、瘀血密切相关,且文献研究结果及导师临床经验均表明以补肾益精、健脾化痰、活血化瘀为治疗原则选方遣药治疗本病,疗效肯定,具有标本兼治的优势。
[Abstract]:Objective: to compare the clinical experience of TCM in treating vascular cognitive disorder and its clinical experience compared with the clinical experience of tutor in treating this disease with the method of tonifying kidney and removing phlegm and activating blood circulation, and to verify the clinical use of drugs with the results of literature study. And broaden the treatment ideas to provide guidance for clinical use, in order to obtain better results in clinical practice in the future. Materials and methods: 106 clinical literatures were collected on the treatment of vascular cognitive impairment with traditional Chinese medicine (TCM), the treatment of syndrome differentiation and medication were sorted out, and the relevant database was established, which was based on the theory of syndrome differentiation. Microsoft Excel software was used to process the data and analyze the syndrome differentiation and drug use rule of literature treatment of this disease. Based on the clinical practice, Professor Liu Jun summarized the clinical experience of treating vascular cognitive disorder with the method of tonifying kidney, removing phlegm and activating blood circulation. The result is 1: 1. In 106 articles, there were 45 syndromes, 16 general syndromes, 21 treatments and 150 kinds of traditional Chinese medicine. The most common syndromes were deficiency of kidney essence and phlegm and blood stasis block. The most common syndromes and their proportion were blood stasis 71.70g, phlegm 43.40g, essence deficiency 42.45. the most common syndromes were kidney. The common treatment methods and their proportion were as follows: promoting blood circulation and removing blood stasis: 96.23C; invigorating spleen and resolving phlegm 47.17; tonifying the kidney and tonifying essence 38.68; The most commonly used single drug is Acorus calamus. Of the 150 herbs involved, 鑽,
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