疏肝解郁安神法治疗心脏神经症（气滞湿阻证）的临床研究
发布时间：2018-07-17 07:40
【摘要】：目的:通过临床病例分析,观察疏肝解郁安神法治疗心脏神经症(气滞湿阻证)的临床疗效。方法:采用临床随机、对照观察的方法,对2014年4月至2015年10月在长春中医药大学第一附属医院心内科姜丽红教授门诊就诊,并明确诊断为心脏神经症(气滞湿阻证)的患者72例,剔除脱落者作为临床观察对象,随机分成2组,实验组36例给予疏肝解郁安神法中药汤剂口服,对照组36例给予逍遥散汤剂口服。以14天为一个疗程,连续治疗2个疗程,随访一个月,观察并采集治疗前、后每个患者详细的临床症状、HAMA评分等变化,之后采用SPSS16.0软件将各个研究对象的评分数据录入数据库,采用统计描述,t检验等方法,评价疏肝解郁安神法对心脏神经症的临床疗效。结果:两组患者用药前年龄、性别、病程、肝肾功能基数比较,P0.05,组间无差异,无统计学意义,具有可比性;用药前2组HAMA评分比较,经t检验P=0.5350.05,无统计学意义,具有可比性;用药前心脏神经症躯体化量表SSS评分比较,经卡方检验,P=0.990.05,无统计学意义,具有可比性;用药前2组中医证候评分比较,经t检验P=0.4250.05,无统计学意义,具有可比性;用药后2组HAMA评分明显下降,用药后组内比较P=0.000.05,两组组内比较均有显著差异,有统计学意义,用药后均明显优于用药前;用药后组间比较,P=0.0190.05,存在显著差异,有统计学意义,治疗组明显优于对照组;用药后两组中医证候评分组间与组内比较,P0.05,均有显著差异,有统计学意义,用药后明显优于用药前、治疗组明显优于对照组;用药后两组心脏神经症SSS评分比较,P=0.0130.05,存在显著差异,有统计学意义。综上,疏肝解郁安神法治疗心脏神经症(气滞湿阻证)在临床上疗效显著,用药前后比较、用药后组间比较均有差异(P0.05),其治疗组临床疗效明显优于对照组。结论:采用疏肝解郁安神法治疗心脏神经症,能明显降低HAMA评分、中医症候疗效评分以及躯体化量表SSS评分;疏肝解郁安神法对心脏神经症(气滞湿阻证)的临床疗效显著,治疗组明显优于对照组,此临床研究有意义。
[Abstract]:Objective: to observe the clinical effect of soothing the liver and relieving depression and soothing the mind in treating cardiac neurosis (qi stagnation and dampness obstruction syndrome) by clinical case analysis. Methods: from April 2014 to October 2015, Professor Jiang Lihong, Department of Cardiology, first affiliated Hospital of Changchun University of traditional Chinese Medicine, was enrolled in this study. 72 cases of cardiac neurosis (Qi stagnation and dampness obstruction syndrome) were definitely diagnosed and were randomly divided into 2 groups. 36 cases in the experimental group were treated with traditional Chinese medicine decoction of soothing the liver and relieving depression and tranquilizing the spirit. 36 cases of control group were given Xiaoyao Powder decoction orally. After 14 days as a course of treatment, 2 consecutive courses of treatment were followed up for one month, the changes of Hama scores of each patient were observed and collected before and after the treatment, and then the score data of each patient were entered into the database by SPSS 16.0 software. To evaluate the clinical efficacy of the method of soothing liver and relieving depression and tranquilizing the mind in the treatment of cardiac neurosis by means of statistical description test. Results: there was no difference between the two groups in age, sex, course of disease, liver and kidney function cardinal number (P0.05), there was no difference between the two groups, there was no significant difference in Hama score between the two groups before medication, and there was no statistical significance and comparability between the two groups after t test (P0. 5350.05). The comparison of SSS score of cardiac neurosis somatization scale before medication was not statistically significant and comparable by chi-square test (P0. 990.05), and the comparison of TCM syndromes score between the two groups before medication was not statistically significant and comparable by t test (P0. 4250. 05). The Hama score of the two groups decreased obviously after the treatment, and the comparison between the two groups was 0.000.05. there was significant difference between the two groups, there was significant difference between the two groups, and the difference between the two groups was obviously better than that before the treatment, and there was a significant difference between the two groups after the use of the drug, there was significant difference between the two groups, and there was a significant difference between the two groups. The treatment group was significantly better than the control group, the two groups after the treatment of TCM syndrome scores between the group and the group compared with P0.05, there was significant difference, there was statistical significance, the treatment group was significantly better than before medication, the treatment group was significantly better than the control group. The SSS score of cardiac neurosis in the two groups was significantly higher than that in the control group (P < 0. 0130. 05). To sum up, the method of soothing the liver and relieving depression and tranquilizing the mind in the treatment of cardiac neurosis (qi stagnation and dampness obstruction syndrome) has a significant clinical effect, the comparison before and after the treatment, the comparison between the groups after medication have differences (P0.05), the clinical efficacy of the treatment group is significantly better than that of the control group. Conclusion: the treatment of cardiac neurosis with the method of soothing the liver and relieving the depression and tranquilizing the mind can obviously reduce the score of Hama, the curative effect of TCM and the score of SSS of somatization, and the clinical effect of the method of soothing the liver and relieving the depression and tranquilizing the mind in the treatment of cardiac neurosis (qi stagnation and dampness obstruction syndrome) is remarkable. The treatment group is obviously superior to the control group, this clinical study is meaningful.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.7
本文编号：2129634
[Abstract]:Objective: to observe the clinical effect of soothing the liver and relieving depression and soothing the mind in treating cardiac neurosis (qi stagnation and dampness obstruction syndrome) by clinical case analysis. Methods: from April 2014 to October 2015, Professor Jiang Lihong, Department of Cardiology, first affiliated Hospital of Changchun University of traditional Chinese Medicine, was enrolled in this study. 72 cases of cardiac neurosis (Qi stagnation and dampness obstruction syndrome) were definitely diagnosed and were randomly divided into 2 groups. 36 cases in the experimental group were treated with traditional Chinese medicine decoction of soothing the liver and relieving depression and tranquilizing the spirit. 36 cases of control group were given Xiaoyao Powder decoction orally. After 14 days as a course of treatment, 2 consecutive courses of treatment were followed up for one month, the changes of Hama scores of each patient were observed and collected before and after the treatment, and then the score data of each patient were entered into the database by SPSS 16.0 software. To evaluate the clinical efficacy of the method of soothing liver and relieving depression and tranquilizing the mind in the treatment of cardiac neurosis by means of statistical description test. Results: there was no difference between the two groups in age, sex, course of disease, liver and kidney function cardinal number (P0.05), there was no difference between the two groups, there was no significant difference in Hama score between the two groups before medication, and there was no statistical significance and comparability between the two groups after t test (P0. 5350.05). The comparison of SSS score of cardiac neurosis somatization scale before medication was not statistically significant and comparable by chi-square test (P0. 990.05), and the comparison of TCM syndromes score between the two groups before medication was not statistically significant and comparable by t test (P0. 4250. 05). The Hama score of the two groups decreased obviously after the treatment, and the comparison between the two groups was 0.000.05. there was significant difference between the two groups, there was significant difference between the two groups, and the difference between the two groups was obviously better than that before the treatment, and there was a significant difference between the two groups after the use of the drug, there was significant difference between the two groups, and there was a significant difference between the two groups. The treatment group was significantly better than the control group, the two groups after the treatment of TCM syndrome scores between the group and the group compared with P0.05, there was significant difference, there was statistical significance, the treatment group was significantly better than before medication, the treatment group was significantly better than the control group. The SSS score of cardiac neurosis in the two groups was significantly higher than that in the control group (P < 0. 0130. 05). To sum up, the method of soothing the liver and relieving depression and tranquilizing the mind in the treatment of cardiac neurosis (qi stagnation and dampness obstruction syndrome) has a significant clinical effect, the comparison before and after the treatment, the comparison between the groups after medication have differences (P0.05), the clinical efficacy of the treatment group is significantly better than that of the control group. Conclusion: the treatment of cardiac neurosis with the method of soothing the liver and relieving the depression and tranquilizing the mind can obviously reduce the score of Hama, the curative effect of TCM and the score of SSS of somatization, and the clinical effect of the method of soothing the liver and relieving the depression and tranquilizing the mind in the treatment of cardiac neurosis (qi stagnation and dampness obstruction syndrome) is remarkable. The treatment group is obviously superior to the control group, this clinical study is meaningful.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.7
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