海艾汤加减方外泡联合中药内服治疗寻常型银屑病（血瘀证）疗效观察

发布时间：2018-07-17 08:43

【摘要】：目的：比较海艾汤加减方外泡联合中药内服与单独中药内服治疗寻常型银屑病(血瘀证)的疗效差异。方法：将60例挑选合格的寻常型银屑病(血瘀证)患者随机分为2组,即治疗组30例,对照组30例。对照组早晚饭后各温服中药汤剂一次(每日一剂)并外用丝塔芙保湿润肤露(每日2次,全身涂抹)；治疗组则同时每天加用海艾汤加减方泡澡30分钟,且水温以个人自身耐受为度,大概40℃。一个疗程4周,共用药3个疗程。治疗结束后参照PAST标准对皮损面积和严重程度进行评分,参照根据《中药新药临床研究指导原则》制定的症状评估表对临床症状进行评分,并记录用药期间出现的不良反应。结果：1)治疗组总有效率可达51.72%,对照组总有效率则为23.08%,且两组疗效有统计学差别,可见治疗组疗效显著优于对照组；2)治疗结束后,治疗组主要临床症状显著改善,且两组对比存在统计学差异。3)两组在整个治疗过程中均未出现不良反应,不存在统计学差异；结论：海艾汤加减方外泡联合中药内服治疗血瘀型寻常型银屑病的疗效和主要临床症状的改善情况均明显比对照组好,而且没有发生不良反应。所以,海艾汤加减方外泡可增强中药内服治疗寻常型银屑病(血瘀证)的疗效,毒副作用小,值得推广。
[Abstract]:Objective: To compare the curative effects of the treatment of 60 cases of psoriasis vulgaris (blood stasis syndrome) randomly into 2 groups, that is, 30 cases in the treatment group and 30 cases in the control group. Day one) and external use of silk moisturizing moisturizing lotion (2 times a day, whole body smear); treatment group combined with a daily use of AIDS soup plus subtraction baths for 30 minutes, and the temperature of individual tolerance, about 40 degrees. A course of 4 weeks, 3 courses of common medicine. After the end of the treatment, the area and severity of skin lesions were evaluated with reference to the PAST standard. According to the symptom assessment table made according to the guiding principles of clinical research of Chinese medicine and new medicine, the clinical symptoms were scored and the adverse reactions were recorded during the medication. Results: 1) the total effective rate of the treatment group was 51.72%, the total effective rate of the control group was 23.08%, and the two groups had statistical difference, and the curative effect of the treatment group was significantly better than that of the control group. 2) 2) after the treatment, the main clinical symptoms of the treatment group improved significantly, and there was a statistical difference between the two groups. The two groups had no adverse reactions in the whole treatment process, and there was no statistical difference. Conclusion: the curative effect and main clinical symptoms of the treatment of blood stasis type psoriasis vulgaris with the combined treatment of the decoction of AI and the Chinese herbal medicine in the two groups were not found in the whole treatment process. The improvement was obviously better than that of the control group, and there was no adverse reaction. Therefore, the effect of the treatment of Chinese herbal medicine on the treatment of psoriasis vulgaris (blood stasis syndrome) was enhanced.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9

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