骨伤复元汤在胫腓骨开放性骨折骨愈合过程中的疗效观察

发布时间：2018-07-21 12:02

【摘要】：研究目的胫腓骨开放性骨折患者,由于小腿前内侧无肌肉覆盖的解剖特点,患处软组织受损,骨膜破坏,血液流通阻塞不畅,血液供应差,容易引起后期发生骨折延迟愈合或不愈合等并发症。从中医角度,早中期应活血化瘀、消肿止痛、续筋接骨。我院自制中药制剂骨伤复元汤,探究其在胫腓骨开放性骨折骨愈合过程中的作用效果,并分析其临床意义,希望能为胫腓骨开放性骨折患者疾病的治疗康复提供意见。研究方法1.依据临床科研方法学,就山东中医药大学附属文登整骨医院2014年1月至2015年1月份就诊的100例胫腓骨开放性骨折的患者资料进行分析和研究。2.采用随机分类的方式,将100例患者随机抽取号码牌,奇数分为观察组,偶数分为对照组。两组患者入院后急诊清创,都采用临床常规的外固定架进行固定,术后均给予抗生素常规消炎治疗。3.观察组在骨折术后早、中期能进食时开始服用我院自制中药骨伤复元汤,早晚各1/2剂,共服用4周。方以活血化瘀、凉血消肿止痛、祛瘀生新药为主;对照组早、中期静滴注射用复方骨肽作为对比。晚期两组都口服相同的接骨药。4.比较两组患者术后的治疗情况,同时术后随访患者4~10个月,平均6个月。同时,观察对照组与观察组患者的临床症状消失时间、愈合时间、血液动力学角度以及并发症等,记录结果并采用统计学的方法进行分析处理。研究结果1.观察组患肢肿胀和疼痛消失时间能够明显缩短。2.观察组患者的PT和APTT延长,血清中纤维蛋白原含量(FIB)降低,能够改善血液粘稠度,防止下肢静脉血栓形成。3.观察组患肢的愈合时间能够明显缩短,骨不愈合率降低。研究结论胫腓骨开放性骨折的治疗以患者术后容易出现骨折延迟愈合或不愈合、下肢静脉血栓形成等并发症较多,以中医学上的观点,在骨折早期,瘀阻经络,不通则痛,应活血化瘀、消肿止痛;在骨折中期祛瘀生新,续筋接骨;在骨折后期补益肝肾、促进骨折愈合。活血化瘀、消肿止痛、祛瘀生新,续筋接骨这是中医治疗开放性骨折早中期的主要方法。总结来说,在骨折早、中期应用活血化瘀、消肿止痛、祛瘀生新药物对于治疗开放性骨折能够缩短肿胀、疼痛时间,能够明显缩短骨折愈合的时间,降低术后下肢静脉血栓形成,应当引起广大医学卫生工作者的关注。
[Abstract]:Objective to study the dissection of the open fracture of the tibia and fibula, due to the dissection of the medial calf medial muscle, the damage of the soft tissue of the affected area, the destruction of the periosteum, the poor circulation of the blood, the poor blood supply, and the complications such as delayed union or non Union in the later period. To explore the effect of its effect on bone healing process of open fracture of tibia and fibula, and analyze its clinical significance, and hope to provide advice for the treatment and rehabilitation of the patients with open fracture of tibia and fibula. Research method 1. according to the clinical science research law, the Wendeng whole affiliated to the Shandong University of Traditional Chinese Medicine. The data of 100 cases of open fracture of tibia and fibula in bone hospital from January 2014 to January 2015 were analyzed and studied..2. was randomly divided into 100 cases, the odd number was divided into the observation group and the even number was divided into the control group. The two groups of patients were treated for acute debridement after admission to the hospital, and the clinical routine external fixators were used. After the operation, the.3. observation group was given antibiotics routine antiphlogistic treatment group after the fracture operation early after the fracture operation and the middle period can be taken to take our home made Chinese medicine bone injury compound soup. Early and late, each 1/2 agent was taken for 4 weeks. In the two groups, the two groups were taken orally with the same bone medicine to compare the treatment of the two groups after the operation, and the patients were followed up for an average of 6 months for 4~10 months. At the same time, the clinical symptoms disappeared, the healing time, the hemodynamic angle and the complications were observed in the control group and the observation group, and the results were recorded and the statistical methods were used for the score. 1. observation group 1. observation group affected limb swelling and pain disappearance time can obviously shorten the PT and APTT prolongation of the patients in the observation group, the decrease of serum fibrinogen content (FIB), improve the blood viscosity, prevent the healing time of the affected limb in the.3. observation group of the lower extremities to be significantly shortened and the bone nonunion rate lower. Conclusion the treatment of open fracture of tibia and fibula is prone to delayed union or nonunion after operation, and more complications such as the formation of venous thrombosis in the lower extremities. Promoting the liver and kidney to promote the healing of fracture. It is the main method of traditional Chinese medicine to treat open fracture in the middle and middle period of traditional Chinese medicine. It is the main method of Chinese medicine to treat open fracture in the early middle period. The time of fracture healing and the reduction of postoperative venous thrombosis of lower extremity should arouse the attention of medical workers.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R274.1

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