加味安神定志颗粒治疗失眠（心胆气虚型）的临床研究

发布时间：2018-07-23 11:14

【摘要】：目的:通过对心胆气虚型失眠的病因病机的探索,观察加味安神定志颗粒治疗心胆气虚型失眠患者的临床疗效,验证加味安神定志颗粒治疗失眠(心胆气虚型)的有效性。方法:本次研究对象于2015年2月至2016年2月就诊于河南中医药大学第一附属医院脑病三区门诊的失眠患者中筛选,将符合本次课题选取标准的60例心胆气虚型失眠患者,随机分为治疗组30例,对照组30例。对照组30例给予右佐匹克隆片睡前3mg口服,治疗组在对照组的基础上口服加味安神定志颗粒每日1剂,治疗组与对照组均服药4周。两组患者分别于治疗前后进行一次中医症候及匹兹堡睡眠质量指数(PQSI)评分,运用统计学对得出的数据进行分析来评价本研究临床疗效。结果:对记录的数据进行统计学分析,治疗前两组患者性别、年龄、病程、中医症候及PQSI评分均无显著性差异(P0.05),提示具有可比性。治疗后统计结果提示治疗组在降低PSQI评分及中医症候评分,改善患者睡眠质量、日间功能障碍方面优于对照组(P0.05)。治疗组总有效率为93.33%,对照组为83.33%,对比具有统计学意义(P0.05)。结论:加味安神定志颗粒联合右佐匹克隆片治疗失眠(心胆气虚型)具有较好的临床效果,在改善患者睡眠质量、日间功能障碍及中医症候方面提示明显优于单用右佐匹克隆片组。
[Abstract]:Objective: to explore the etiology and pathogenesis of insomnia of heart and gallbladder qi deficiency, observe the clinical effect of Jiawei Anshen Dingzhi granule in treating insomnia of heart and gallbladder qi deficiency, and verify the effectiveness of Jiawei Anshen Dingzhi granule in treating insomnia (heart and gallbladder qi deficiency). Methods: from February 2015 to February 2016, 60 patients with insomnia of heart and gallbladder qi deficiency type were selected from the outpatient clinic of the first affiliated Hospital of Henan University of traditional Chinese Medicine in the third District of Encephalopathy, which were selected from February 2015 to February 2016. They were randomly divided into treatment group (n = 30) and control group (n = 30). The control group (30 cases) were given 3mg before bedtime, and the treatment group took 1 dose of Jiawei Anshen Dingzhi granule daily on the basis of the control group. The treatment group and the control group were treated for 4 weeks. Two groups of patients before and after the treatment of TCM symptoms and Pittsburgh Sleep quality Index (PQSI) score statistical analysis of the data obtained to evaluate the clinical efficacy of this study. Results: there were no significant differences in gender, age, course of disease, TCM symptom and PQSI score between the two groups before treatment (P0.05). The statistical results showed that the treatment group was superior to the control group in reducing PSQI score and TCM symptom score, improving patients' sleep quality and daytime dysfunction (P0.05). The total effective rate was 93.33 in the treatment group and 83.33 in the control group. The comparison was statistically significant (P0.05). Conclusion: Jiawei Anshen Dingzhi granule combined with right zopicone tablet has good clinical effect in treating insomnia (heart and gallbladder qi deficiency type) and can improve the sleeping quality of patients. The results showed that the daytime dysfunction and TCM symptoms were better than that of RZP alone.
【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.23

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